Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50006938
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50454526(CHEMBL3138293)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro for inhibition of [35S]TBPS binding in rat brain cortical membranes in the presence of 5 uM GABA in two-component inhibition curveMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50055953(1-[(3R,5R,10S,13S,17S)-3-Hydroxy-3-(2-hydroxy-phen...)
Affinity DataIC50:  5.10E+3nMAssay Description:In vitro inhibition of [35S]-TBPS binding to Gamma-aminobutyric acid A receptor in rat brain cortical membranes in the presence of 5 uM GABA (low aff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50454526(CHEMBL3138293)
Affinity DataEC50:  31nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50454529(CHEMBL3138315)
Affinity DataEC50: >1.00E+3nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50055953(1-[(3R,5R,10S,13S,17S)-3-Hydroxy-3-(2-hydroxy-phen...)
Affinity DataEC50:  340nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50454531(CHEMBL3138433)
Affinity DataEC50:  8.20nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50454528(CHEMBL3138292)
Affinity DataEC50: >1.00E+3nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50454527(CHEMBL3138291)
Affinity DataEC50:  18nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50055963(1-[(3R,5R,10S,13S,17S)-3-(4-Acetyl-phenylethynyl)-...)
Affinity DataEC50:  6.60nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed