Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 1664
TargetMatrix metalloproteinase-9(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 8465BDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  8nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 8465BDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  20nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13122BDBM13122((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataKi:  23nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13133BDBM13133((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataKi:  28nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13121BDBM13121((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataKi:  29nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13127BDBM13127((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataKi:  31nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 8465BDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  33nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13126BDBM13126(CHEMBL85030 | (2R)-2-[benzyl(4-methoxybenzene)sulf...)
Affinity DataKi:  34nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13119BDBM13119(CHEMBL314064 | (2R)-2-[benzyl(4-methoxybenzene)sul...)
Affinity DataKi:  36nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13100BDBM13100(2-[(2-cyclohexylethyl)(4-methoxybenzene)sulfonamid...)
Affinity DataKi:  38nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13135BDBM13135((2R,3S)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-...)
Affinity DataKi:  39nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13141BDBM13141((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  42nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 8465BDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataKi:  43nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13134BDBM13134((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-3-cyc...)
Affinity DataKi:  44nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13137BDBM13137((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  46nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13131BDBM13131((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-3-(te...)
Affinity DataKi:  48nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13136BDBM13136(2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-...)
Affinity DataKi:  50nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13088BDBM13088(2-[(4-butoxybenzene)(2-methylpropyl)sulfonamido]-N...)
Affinity DataKi:  58nM ΔG°:  -43.0kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13099BDBM13099(2-[(cyclohexylmethyl)(4-methoxybenzene)sulfonamido...)
Affinity DataKi:  61nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13091BDBM13091(2-{[4-(cyclohexylmethoxy)benzene](2-methylpropyl)s...)
Affinity DataKi:  61nM ΔG°:  -42.8kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13090BDBM13090(2-{[4-(hexyloxy)benzene](2-methylpropyl)sulfonamid...)
Affinity DataKi:  63nM ΔG°:  -42.8kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13132BDBM13132(2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-...)
Affinity DataKi:  65nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13095BDBM13095(N-hydroxy-2-[(4-methoxybenzene)(2-phenylethyl)sulf...)
Affinity DataKi:  66nM ΔG°:  -42.6kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13130BDBM13130((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-6-(di...)
Affinity DataKi:  69nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13129BDBM13129(benzyl N-[(5R)-5-[benzyl(4-methoxybenzene)sulfonam...)
Affinity DataKi:  70nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 11331BDBM11331(CGS 27023A Analog 22 | 2-[benzyl(4-methoxybenzene)...)
Affinity DataKi:  70nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13111BDBM13111(N-hydroxy-2-[(4-methoxybenzene)[(3-methoxyphenyl)m...)
Affinity DataKi:  70nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13120BDBM13120(2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-...)
Affinity DataKi:  71nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13089BDBM13089(N-hydroxy-2-{[4-(3-methylbutoxy)benzene](2-methylp...)
Affinity DataKi:  78nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13140BDBM13140((2R)-6-(dimethylamino)-N-hydroxy-2-[(4-methoxybenz...)
Affinity DataKi:  81nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13128BDBM13128((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataKi:  85nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 11337BDBM11337(CHEMBL316169 | 2-[benzyl(4-methoxybenzene)sulfonam...)
Affinity DataKi:  86nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13115BDBM13115(N-hydroxy-2-[(4-methoxybenzene)(pyridin-2-ylmethyl...)
Affinity DataKi:  90nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13125BDBM13125(2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-...)
Affinity DataKi:  92nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13098BDBM13098(N-hydroxy-2-[(4-methoxybenzene)(3-methylbutyl)sulf...)
Affinity DataKi:  94nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13104BDBM13104(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)
Affinity DataKi:  94nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13097BDBM13097(N-hydroxy-2-[(4-methoxybenzene)(4-phenylbutyl)sulf...)
Affinity DataKi:  100nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13105BDBM13105(N-hydroxy-2-[(4-methoxybenzene)[(4-methoxyphenyl)m...)
Affinity DataKi:  104nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13123BDBM13123((2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hyd...)
Affinity DataKi:  104nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13106BDBM13106(N-hydroxy-2-[(4-methoxybenzene)[(4-phenylphenyl)me...)
Affinity DataKi:  107nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13114BDBM13114(N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl...)
Affinity DataKi:  113nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13096BDBM13096(N-hydroxy-2-[(4-methoxybenzene)(3-phenylpropyl)sul...)
Affinity DataKi:  125nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13080BDBM13080(N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sul...)
Affinity DataKi:  133nM ΔG°:  -40.8kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13116BDBM13116(N-hydroxy-2-[(4-methoxybenzene)(quinolin-2-ylmethy...)
Affinity DataKi:  134nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13118BDBM13118(CHEMBL314204 | (2S)-2-[benzyl(4-methoxybenzene)sul...)
Affinity DataKi:  141nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13112BDBM13112(N-hydroxy-2-[(4-methoxybenzene)[(3,4,5-trimethoxyp...)
Affinity DataKi:  151nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13113BDBM13113(N-hydroxy-2-[(4-methoxybenzene)(pyridin-4-ylmethyl...)
Affinity DataKi:  192nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13109BDBM13109(N-hydroxy-2-[(4-methoxybenzene)[2-(morpholin-4-yl)...)
Affinity DataKi:  236nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13107BDBM13107(N-hydroxy-2-[(4-methoxybenzene)(2,2,2-trifluoroeth...)
Affinity DataKi:  305nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13092BDBM13092(N-hydroxy-2-[(2-methylpropyl)[4-(propan-2-yloxy)be...)
Affinity DataKi:  336nM ΔG°:  -38.4kJ/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
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