Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50007471
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063780(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063779(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063780(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063781(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  95nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063781(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  95nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063783(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063795(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzo[b]t...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063787(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  220nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063783(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063796(1-(8-tert-Butyl-1,4,4-trimethyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063793(1-(8-tert-Butyl-4,4-dimethyl-thiochroman-6-yl)-pen...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063793(1-(8-tert-Butyl-4,4-dimethyl-thiochroman-6-yl)-pen...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063795(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzo[b]t...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063779(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063796(1-(8-tert-Butyl-1,4,4-trimethyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063783(1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063797(1-(7-tert-Butyl-2,3-dihydro-benzofuran-5-yl)-4-cyc...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063798(4-Cyclopropyl-1-(3-ethyl-3-methyl-2,3-dihydro-benz...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063780(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063787(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063791(4-Cyclopropyl-1-(3,3-dimethyl-2,3-dihydro-benzofur...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063787(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063781(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063779(1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063797(1-(7-tert-Butyl-2,3-dihydro-benzofuran-5-yl)-4-cyc...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063797(1-(7-tert-Butyl-2,3-dihydro-benzofuran-5-yl)-4-cyc...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063798(4-Cyclopropyl-1-(3-ethyl-3-methyl-2,3-dihydro-benz...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063798(4-Cyclopropyl-1-(3-ethyl-3-methyl-2,3-dihydro-benz...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063794(1-(7-Cyclopentyl-3,3-dimethyl-2,3-dihydro-benzofur...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063791(4-Cyclopropyl-1-(3,3-dimethyl-2,3-dihydro-benzofur...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063794(1-(7-Cyclopentyl-3,3-dimethyl-2,3-dihydro-benzofur...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed