Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50007480
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.200nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.210nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.300nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.300nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.390nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  1.20nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  1.60nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  1.90nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataKi:  2nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  2nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetAlpha-1D adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  2.40nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  3.40nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataKi:  3.5nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  3.90nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  4.20nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataKi:  5.40nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataKi:  7nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataKi:  25nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataKi:  34nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataKi:  73nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataKi:  78nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  191nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataKi:  250nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  294nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  328nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataKi:  420nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataKi:  500nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataKi:  510nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataKi:  580nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  620nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataKi:  630nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataKi:  830nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50455469(CHEMBL2079655)
Affinity DataKi:  1.05E+3nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataKi:  1.50E+3nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataKi:  1.70E+3nMAssay Description:Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adrenergi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50455469(CHEMBL2079655)
Affinity DataKi:  2.25E+3nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50455469(CHEMBL2079655)
Affinity DataKi:  2.90E+3nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataIC50:  3.20nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataIC50:  3.20nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataIC50:  8.80nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataIC50:  9.30nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat spleen Alpha-1B adrenergic receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataIC50:  9.30nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat liver Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataIC50:  14nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat spleen Alpha-1B adrenergic receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063906((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-1-(f...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat liver Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataIC50:  31nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataIC50:  340nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat prostate Alpha-1A adrenergic receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50063907((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-te...)
Affinity DataIC50:  590nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the human prostate Alpha-1A adrenergic receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50063908((S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-pipe...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat spleen Alpha-1B adrenergic receptor subtype.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Displayed 1 to 50 (of 55 total ) | Next | Last >>
Jump to: