Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50036716
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064106BDBM50064106({[(S)-2-Biphenyl-4-yl-1-(2H-tetrazol-5-yl)-ethylam...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064109BDBM50064109({1-[2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylamin...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064114BDBM50064114((S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064125BDBM50064125((S)-3-Cyclohexyl-2-[(S)-5-(2,4-difluoro-phenyl)-2-...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064096BDBM50064096({[(S)-4-(2-Fluoro-phenyl)-1-(2H-tetrazol-5-yl)-but...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064109BDBM50064109({1-[2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylamin...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064124BDBM50064124((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064113BDBM50064113({[(S)-1-(2-Biphenyl-4-yl-ethylcarbamoyl)-4-(2,4-di...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064112BDBM50064112((S)-5-(2-Fluoro-phenyl)-2-[(S)-5-(2-fluoro-phenyl)...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251742BDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064099BDBM50064099({[(S)-1-(2-Biphenyl-4-yl-ethylcarbamoyl)-4-(2-fluo...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064123BDBM50064123({[(S)-4-(2,4-Difluoro-phenyl)-1-(2-naphthalen-1-yl...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064128BDBM50064128({[(S)-1-[2-(4-Bromo-phenyl)-ethylcarbamoyl]-4-(2,4...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064120BDBM50064120((S)-2-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonomet...)
Affinity DataIC50: 51nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064118BDBM50064118({[(S)-4-(2,4-Difluoro-phenyl)-1-(2-naphthalen-2-yl...)
Affinity DataIC50: 53nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064129BDBM50064129((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 56nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064101BDBM50064101({[(S)-1-[3-(2-Amino-ethyl)-1H-indol-2-ylcarbamoyl]...)
Affinity DataIC50: 76nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064105BDBM50064105({(S)-3-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonome...)
Affinity DataIC50: 82nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064104BDBM50064104((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064131BDBM50064131({[(S)-4-(2,4-Difluoro-phenyl)-1-phenethylcarbamoyl...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064116BDBM50064116({[(S)-1-[2-(4-Bromo-phenyl)-ethylcarbamoyl]-4-(2-f...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064111BDBM50064111({[(S)-1-[3-(2-Amino-ethyl)-1H-indol-2-ylcarbamoyl]...)
Affinity DataIC50: 111nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064130BDBM50064130((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064121BDBM50064121({[(S)-4-(2-Fluoro-phenyl)-1-(2-naphthalen-1-yl-eth...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064107BDBM50064107({[(S)-4-(2,4-Difluoro-phenyl)-1-(3-methyl-butylcar...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064103BDBM50064103({[(S)-4-(2,4-Difluoro-phenyl)-1-(3-phenyl-propylca...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064096BDBM50064096({[(S)-4-(2-Fluoro-phenyl)-1-(2H-tetrazol-5-yl)-but...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064126BDBM50064126(({(S)-4-(2,4-Difluoro-phenyl)-1-[2-(3,4-dimethoxy-...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064115BDBM50064115((S)-5-(2,4-Difluoro-phenyl)-2-(phosphonomethyl-ami...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064108BDBM50064108({[(S)-4-Phenyl-1-(2H-tetrazol-5-yl)-but-3-ynylamin...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064100BDBM50064100({[(S)-4-(2-Fluoro-phenyl)-1-phenethylcarbamoyl-but...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064122BDBM50064122((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064127BDBM50064127((S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064119BDBM50064119({[(S)-1-Benzylcarbamoyl-4-(2-fluoro-phenyl)-but-3-...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064114BDBM50064114((S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064097BDBM50064097({[(S)-4-(2,4-Difluoro-phenyl)-1-(2-pyridin-2-yl-et...)
Affinity DataIC50: 310nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064117BDBM50064117((S)-2-[(S)-5-(3-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064117BDBM50064117((S)-2-[(S)-5-(3-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 407nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064106BDBM50064106({[(S)-2-Biphenyl-4-yl-1-(2H-tetrazol-5-yl)-ethylam...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064132BDBM50064132((S)-4-Methyl-2-[(S)-5-phenyl-2-(phosphonomethyl-am...)
Affinity DataIC50: 510nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064108BDBM50064108({[(S)-4-Phenyl-1-(2H-tetrazol-5-yl)-but-3-ynylamin...)
Affinity DataIC50: 590nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064103BDBM50064103({[(S)-4-(2,4-Difluoro-phenyl)-1-(3-phenyl-propylca...)
Affinity DataIC50: 640nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064105BDBM50064105({(S)-3-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonome...)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064128BDBM50064128({[(S)-1-[2-(4-Bromo-phenyl)-ethylcarbamoyl]-4-(2,4...)
Affinity DataIC50: 860nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064132BDBM50064132((S)-4-Methyl-2-[(S)-5-phenyl-2-(phosphonomethyl-am...)
Affinity DataIC50: 948nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251742BDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064129BDBM50064129((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064124BDBM50064124((S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064125BDBM50064125((S)-3-Cyclohexyl-2-[(S)-5-(2,4-difluoro-phenyl)-2-...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064113BDBM50064113({[(S)-1-(2-Biphenyl-4-yl-ethylcarbamoyl)-4-(2,4-di...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
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