Compile Data Set for Download or QSAR
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Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50036631
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065404((R)-N-((S)-5-Benzenesulfonylamino-1-formyl-pentyl)...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065404((R)-N-((S)-5-Benzenesulfonylamino-1-formyl-pentyl)...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065398((R)-3-Benzyloxy-N-[(S)-1-(4-benzyloxy-benzyl)-2-ox...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065398((R)-3-Benzyloxy-N-[(S)-1-(4-benzyloxy-benzyl)-2-ox...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065407((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065401((S)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzylsulfanyl-...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065401((S)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzylsulfanyl-...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065399((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065407((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014577(CHEMBL286722 | MDL-2170 | Z-Val-Phe-H | [(S)-1-((S...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065411((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065412((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-(th...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065399((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065405((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-(1H-indol-3-yl)...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065408((S)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065403((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065403((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065404((R)-N-((S)-5-Benzenesulfonylamino-1-formyl-pentyl)...)
Affinity DataKi:  17nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065413((R)-2-Benzenesulfonylamino-N-((S)-1-benzyl-2-oxo-e...)
Affinity DataKi:  22nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  23nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014577(CHEMBL286722 | MDL-2170 | Z-Val-Phe-H | [(S)-1-((S...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065414((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065402((R)-2-Methanesulfonylamino-4-methyl-pentanoic acid...)
Affinity DataKi:  29nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065407((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataKi:  32nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065397((R)-3-Benzyloxy-N-((S)-1-formyl-propyl)-2-methanes...)
Affinity DataKi:  36nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50408434(CHEMBL2114233)
Affinity DataKi:  41nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065401((S)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzylsulfanyl-...)
Affinity DataKi:  41nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065399((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataKi:  44nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065398((R)-3-Benzyloxy-N-[(S)-1-(4-benzyloxy-benzyl)-2-ox...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065406((R)-3-Benzyloxy-N-((S)-1-formyl-3-methyl-butyl)-2-...)
Affinity DataKi:  66nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065403((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065409((S)-3-((R)-3-Benzyloxy-2-methanesulfonylamino-prop...)
Affinity DataKi:  130nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065410((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-(me...)
Affinity DataKi:  370nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50014577(CHEMBL286722 | MDL-2170 | Z-Val-Phe-H | [(S)-1-((S...)
Affinity DataIC50:  300nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataIC50:  400nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065404((R)-N-((S)-5-Benzenesulfonylamino-1-formyl-pentyl)...)
Affinity DataIC50:  400nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065399((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataIC50:  500nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065403((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataIC50:  600nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065398((R)-3-Benzyloxy-N-[(S)-1-(4-benzyloxy-benzyl)-2-ox...)
Affinity DataIC50:  700nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065407((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataIC50:  700nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065401((S)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzylsulfanyl-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed