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Found 31 Enz. Inhib. hit(s) with all data for entry = 50007737
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50:  23nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 0 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50:  36nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  47nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066997((3aS,6R)-6-Allyl-4-methanesulfonyl-5-oxo-hexahydro...)
Affinity DataIC50:  56nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  69nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  74nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50:  88nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  336nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 0 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50:  980nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  3.60E+3nMAssay Description:The compound was tested for inhibition of cathepsin G with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  4.00E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  4.86E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50:  1.15E+4nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  1.28E+4nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 0 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  1.59E+4nMAssay Description:The compound was tested for inhition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066997((3aS,6R)-6-Allyl-4-methanesulfonyl-5-oxo-hexahydro...)
Affinity DataIC50:  4.06E+4nMAssay Description:The compound was tested for inhition of thrombin with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066997((3aS,6R)-6-Allyl-4-methanesulfonyl-5-oxo-hexahydro...)
Affinity DataIC50:  4.06E+4nMAssay Description:The compound was tested for inhibition of cathepsin G with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066997((3aS,6R)-6-Allyl-4-methanesulfonyl-5-oxo-hexahydro...)
Affinity DataIC50:  4.06E+4nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066997((3aS,6R)-6-Allyl-4-methanesulfonyl-5-oxo-hexahydro...)
Affinity DataIC50:  4.06E+4nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  4.46E+4nMAssay Description:The compound was tested for inhition of thrombin with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  4.90E+4nMAssay Description:The compound was tested for inhition of thrombin with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  6.70E+4nMAssay Description:The compound was tested for inhibition of cathepsin G with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50:  7.88E+4nMAssay Description:The compound was tested for inhibition of thrombin with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001((3aS,6R)-6-Allyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested for inhibition of thrombin with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested for inhibition of cathepsin G with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001((3aS,6R)-6-Allyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested for inhibition of thrombin with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001((3aS,6R)-6-Allyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067000((3aS,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 0 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: >2.00E+5nMAssay Description:The compound was tested for inhition of thrombin with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067001((3aS,6R)-6-Allyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: >5.00E+5nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed