Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50048446
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064858BDBM50064858(4-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-phenyl-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064858BDBM50064858(4-[2-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-phenyl-...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216308BDBM50216308(CHEMBL297296)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 320nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216313BDBM50216313(CHEMBL300959)
Affinity DataIC50: 400nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216308BDBM50216308(CHEMBL297296)
Affinity DataIC50: 600nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216322BDBM50216322(CHEMBL301351)
Affinity DataIC50: 700nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216320BDBM50216320(CHEMBL430948)
Affinity DataIC50: 700nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216310BDBM50216310(CHEMBL52224)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216307BDBM50216307(CHEMBL300038)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216309BDBM50216309(CHEMBL301366)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216314BDBM50216314(CHEMBL49351)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216312BDBM50216312(CHEMBL296824)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216311BDBM50216311(CHEMBL300427)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216314BDBM50216314(CHEMBL49351)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216313BDBM50216313(CHEMBL300959)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216322BDBM50216322(CHEMBL301351)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216310BDBM50216310(CHEMBL52224)
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216311BDBM50216311(CHEMBL300427)
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216307BDBM50216307(CHEMBL300038)
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216312BDBM50216312(CHEMBL296824)
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216306BDBM50216306(CHEMBL48221)
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216320BDBM50216320(CHEMBL430948)
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216309BDBM50216309(CHEMBL301366)
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216306BDBM50216306(CHEMBL48221)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details Article
PubMed