Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50008028
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM22541(VUF 9153 | N''-[(4-chlorophenyl)methyl]{[3-(1H-imi...)
Affinity DataKi:  0.180nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070217(CHEMBL15075 | 3-(3-Bromo-4-methoxy-phenyl)-2-[(E)-...)
Affinity DataKi:  0.5nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070214(CHEMBL280076 | GT 2293 | 4-(7,7-Dimethyl-oct-3-yny...)
Affinity DataKi:  0.800nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070220(GT 2286 | CHEMBL274977 | 4-(6-Cyclopentyl-hex-3-yn...)
Affinity DataKi:  0.950nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM7967(CHEMBL14722 | 2-(1-methyl-1H-imidazol-5-yl)ethan-1...)
Affinity DataKi:  1nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  1.5nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070211(GT 2260 | CHEMBL15000 | 4-(6-Cyclohexyl-hex-3-ynyl...)
Affinity DataKi:  2.90nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070216(4-(8-Phenyl-oct-3-ynyl)-1H-imidazole | CHEMBL14811)
Affinity DataKi:  3.5nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070212(4-(7-Methyl-oct-3-ynyl)-1H-imidazole | CHEMBL14497)
Affinity DataKi:  3.70nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  4.30nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070213(GR-175737 | 3-(4-Chloro-benzyl)-5-[2-(1H-imidazol-...)
Affinity DataKi:  7nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070215(4-Hept-3-ynyl-1H-imidazole | CHEMBL276804)
Affinity DataKi:  27nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM86490(CHEMBL14812 | NSC_0 | CAS_0 | GT 2016)
Affinity DataKi:  40nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Gliatech

Curated by ChEMBL
LigandPNGBDBM50070219(4-Hex-3-ynyl-1H-imidazole | CHEMBL14721)
Affinity DataKi:  79nMAssay Description:Antagonistic activity was evaluated against histamine H3 receptor using [3H]- N-alpha-methylhistamine as radioligand in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed