Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 50008044
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059715(4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50070314(7-((3-fluoro-5-(3-hydroxy-6,8-dioxabicyclo[3.2.1]o...)
Affinity DataIC50:  27nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50070310(4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...)
Affinity DataIC50:  36nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50070312(1-Benzyl-4-furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bi...)
Affinity DataIC50:  102nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50070313(7-[3-Fluoro-5-(3-hydroxy-6,8-dioxa-bicyclo[3.2.1]o...)
Affinity DataIC50:  124nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50070308(3-[6-(4-Furan-3-yl-isoquinolin-7-yloxymethyl)-pyri...)
Affinity DataIC50:  1.46E+3nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50070311(1-Furan-3-yl-6-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...)
Affinity DataIC50:  1.96E+3nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50070309(4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa-bicyclo[3.2...)
Affinity DataIC50: >3.00E+3nMAssay Description:Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed