Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50008070
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070457((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-((S)...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070457((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-((S)...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070453((2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070453((2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070455((R)-N*1*-Hydroxy-3-isobutyl-2,2-dimethyl-N*4*-((S)...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070452((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070452((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070462((2S,3R)-2-Allyl-N*4*-{(S)-2-cyclohexyl-1-[2-(4-sul...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070455((R)-N*1*-Hydroxy-3-isobutyl-2,2-dimethyl-N*4*-((S)...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070453((2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070462((2S,3R)-2-Allyl-N*4*-{(S)-2-cyclohexyl-1-[2-(4-sul...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070462((2S,3R)-2-Allyl-N*4*-{(S)-2-cyclohexyl-1-[2-(4-sul...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070463((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070463((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070454(1-[(R)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070454(1-[(R)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070457((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-((S)...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50:  50nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070459((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  52nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070456((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070463((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070451((2S,3R)-2-Allyl-N*4*-((S)-2-cyclohexyl-1-phenethyl...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070459((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  66nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070456((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  91nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50:  95nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070458((R)-2,2-Diallyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070451((2S,3R)-2-Allyl-N*4*-((S)-2-cyclohexyl-1-phenethyl...)
Affinity DataIC50:  110nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070456((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  120nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070451((2S,3R)-2-Allyl-N*4*-((S)-2-cyclohexyl-1-phenethyl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070454(1-[(R)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070455((R)-N*1*-Hydroxy-3-isobutyl-2,2-dimethyl-N*4*-((S)...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070459((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50:  420nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070452((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  480nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070458((R)-2,2-Diallyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070458((R)-2,2-Diallyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Matrix metalloproteinase-3(MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed