Compile Data Set for Download or QSAR
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Found 15 Enz. Inhib. hit(s) with all data for entry = 50034936
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070546(1-(2-{(S)-3-(3,4-Dichloro-phenyl)-1-[2-(3-isopropo...)
Affinity DataIC50:  0.0190nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070548(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3-isopropoxy-p...)
Affinity DataIC50:  0.310nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070554(1'-(2-{3-(3,4-dichlorophenyl)-1-[2-(3-isopropoxyph...)
Affinity DataIC50:  1.90nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070554(1'-(2-{3-(3,4-dichlorophenyl)-1-[2-(3-isopropoxyph...)
Affinity DataIC50:  1.90nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070558(1-(3-(3,4-dichlorophenyl)-3-{2-[1'-methylspiro[1,2...)
Affinity DataIC50:  2nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070552(1-(3-(3,4-dichlorophenyl)-3-{2-[1'-ethylspiro[1,2,...)
Affinity DataIC50:  4.80nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070557(CHEMBL38030 | piperidine analogue)
Affinity DataIC50:  6.30nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070550(1-[3-{2-[1'-benzylspiro[1,2,3,4-tetrahydroisoquino...)
Affinity DataIC50:  16nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366500(CHEMBL1201933)
Affinity DataIC50:  16nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070555(CHEMBL38624 | piperidine analogue)
Affinity DataIC50:  18nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070556(1-{3-(3,4-Dichloro-phenyl)-3-[2-(3,4-dihydro-2H-sp...)
Affinity DataIC50:  31nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070551(1'-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3-isopropoxy-...)
Affinity DataIC50:  54nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070549(CHEMBL39232 | N-[2-(3,4-Dichloro-phenyl)-4-(3,4-di...)
Affinity DataIC50:  58nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366499(CHEMBL1794935)
Affinity DataIC50:  105nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070545(1'-[3-(3,4-dichlorophenyl)-4-methyl(phenyl)carboxa...)
Affinity DataIC50:  710nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed