Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50008231
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071664(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  32nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071667(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Affinity DataIC50:  102nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071666(2-(3,5-Dibromo-4-hydroxy-benzylidene)-5,6-dimethox...)
Affinity DataIC50:  110nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071677(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Affinity DataIC50:  144nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071668(2-(3,5-Dichloro-4-hydroxy-benzylidene)-5,6-dimetho...)
Affinity DataIC50:  310nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071664(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071676(4-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  470nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071665(5-Amino-2-[1-(3,4-dihydroxy-phenyl)-meth-(E)-ylide...)
Affinity DataIC50:  600nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071670(6-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  710nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071669(2-(3,5-Dibromo-4-hydroxy-benzylidene)-indan-1,3-di...)
Affinity DataIC50:  740nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071682(2-[1-(3-Bromo-4-hydroxy-5-methoxy-phenyl)-meth-(E)...)
Affinity DataIC50:  880nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071678(5-Bromo-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071675(2-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071681(2-[1-(3,4-Dihydroxy-phenyl)-meth-(E)-ylidene]-5-me...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071680(2-(3-Bromo-4-hydroxy-5-methoxy-benzylidene)-5,6-di...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071673(5-Amino-2-[1-(4-hydroxy-3,5-dimethoxy-phenyl)-meth...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071667(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071679(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071674(2-[1-(3,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-5-ni...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071671(5,6-Dichloro-2-(4-hydroxy-3-methoxy-benzylidene)-i...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071672(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50067024(2-(3,4-Dihydroxy-benzylidene)-indan-1,3-dione | CH...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071667(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Protein Kinase A (PKA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071683(2-[1-(3,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-4-ni...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50045936((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071664(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Protein Kinase A (PKA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071677(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Protein Kinase A (PKA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50071677(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed