Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50034953
TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071733(CHEMBL413196 | Compound GRP)
Affinity DataKi:  0.0400nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataKi:  0.0680nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  0.150nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071735((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...)
Affinity DataKi:  0.150nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071739((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...)
Affinity DataKi:  0.170nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071750((S)-3-(1H-Indol-3-yl)-2-methyl-N-[1-(4-nitro-pheny...)
Affinity DataKi:  0.300nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071746((S)-2-[3-(4-Cyano-phenyl)-ureido]-3-(1H-indol-3-yl...)
Affinity DataKi:  0.320nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071748((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...)
Affinity DataKi:  0.390nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071736((S)-N-[1-(3,4-Dimethoxy-phenyl)-cyclohexylmethyl]-...)
Affinity DataKi:  0.440nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071743((S)-3-(1H-Indol-3-yl)-N-[1-(4-methoxy-phenyl)-cycl...)
Affinity DataKi:  0.460nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071741((S)-N-[1-(4-Dimethylamino-phenyl)-cyclohexylmethyl...)
Affinity DataKi:  0.520nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071742((S)-N-[1-(4-Ethoxy-phenyl)-cyclohexylmethyl]-3-(1H...)
Affinity DataKi:  0.590nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071738((S)-N-[1-(4-Hydroxy-phenyl)-cyclohexylmethyl]-3-(1...)
Affinity DataKi:  0.620nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071744(AcBB(7-14) | CHEMBL314375)
Affinity DataKi:  0.700nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071737((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(3-nitro-pheny...)
Affinity DataKi:  0.970nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071739((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...)
Affinity DataKi:  1nMAssay Description:Antagonistic activity against cloned human Bombesin receptor bb2 labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells; 0.66-1.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071749((S)-3-(1H-Indol-3-yl)-N-[1-(4-isopropyl-phenyl)-cy...)
Affinity DataKi:  1.5nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  2nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071734((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...)
Affinity DataKi:  2.10nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071744(AcBB(7-14) | CHEMBL314375)
Affinity DataKi:  2.10nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071740((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Affinity DataKi:  2.80nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071753((S)-3-(1H-Indol-3-yl)-2-methyl-N-(1-pyridin-2-yl-c...)
Affinity DataKi:  2.90nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071755((S)-3-(1H-Indol-3-yl)-N-[1-(2-methoxy-phenyl)-cycl...)
Affinity DataKi:  3.40nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071743((S)-3-(1H-Indol-3-yl)-N-[1-(4-methoxy-phenyl)-cycl...)
Affinity DataKi:  3.70nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071742((S)-N-[1-(4-Ethoxy-phenyl)-cyclohexylmethyl]-3-(1H...)
Affinity DataKi:  5.80nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071754((S)-2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-in...)
Affinity DataKi:  6.30nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071750((S)-3-(1H-Indol-3-yl)-2-methyl-N-[1-(4-nitro-pheny...)
Affinity DataKi:  6.40nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071741((S)-N-[1-(4-Dimethylamino-phenyl)-cyclohexylmethyl...)
Affinity DataKi:  9nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071733(CHEMBL413196 | Compound GRP)
Affinity DataKi:  9.10nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071751((S)-3-(1H-Indol-3-yl)-2-[3-(4-isopropyl-phenyl)-ur...)
Affinity DataKi:  9.40nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071735((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...)
Affinity DataKi:  17nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071752((S)-3-(1H-Indol-3-yl)-2-methyl-2-(3-phenyl-ureido)...)
Affinity DataKi:  27nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071738((S)-N-[1-(4-Hydroxy-phenyl)-cyclohexylmethyl]-3-(1...)
Affinity DataKi:  32nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071736((S)-N-[1-(3,4-Dimethoxy-phenyl)-cyclohexylmethyl]-...)
Affinity DataKi:  33nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071749((S)-3-(1H-Indol-3-yl)-N-[1-(4-isopropyl-phenyl)-cy...)
Affinity DataKi:  35nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071746((S)-2-[3-(4-Cyano-phenyl)-ureido]-3-(1H-indol-3-yl...)
Affinity DataKi:  37nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataKi:  56nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071737((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(3-nitro-pheny...)
Affinity DataKi:  85nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071734((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...)
Affinity DataKi:  85nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071748((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...)
Affinity DataKi:  89nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071753((S)-3-(1H-Indol-3-yl)-2-methyl-N-(1-pyridin-2-yl-c...)
Affinity DataKi:  124nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071740((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...)
Affinity DataKi:  149nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071732((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(2-nitro-pheny...)
Affinity DataKi:  184nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071751((S)-3-(1H-Indol-3-yl)-2-[3-(4-isopropyl-phenyl)-ur...)
Affinity DataKi:  273nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071755((S)-3-(1H-Indol-3-yl)-N-[1-(2-methoxy-phenyl)-cycl...)
Affinity DataKi:  404nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071752((S)-3-(1H-Indol-3-yl)-2-methyl-2-(3-phenyl-ureido)...)
Affinity DataKi:  1.10E+3nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071732((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(2-nitro-pheny...)
Affinity DataKi:  1.25E+3nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071754((S)-2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-in...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071739((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...)
Affinity DataIC50:  0.660nMAssay Description:Antagonistic activity against labelled Bombesin receptor bb1 binding sites in rat olfactory bulb by using [125I]- [Tyr] bombesin in presence of [D-Ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071739((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...)
Affinity DataIC50:  16nMAssay Description:Antagonistic activity against labelled Bombesin receptor bb2 binding sites in rat cerebral cortex by using [125I]- [Tyr] bombesin in presence of NMB;...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)