Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50008249
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 20nMAssay Description:Relative inhibition of phosphodiesterase 4 activity and Rolipram binding to PDE4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50216272BDBM50216272(CHEMBL415474)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216262BDBM50216262(CHEMBL90278)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216269BDBM50216269(CHEMBL410340)
Affinity DataIC50: 600nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216284BDBM50216284(CHEMBL420805)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216291BDBM50216291(CHEMBL88948)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50071804BDBM50071804(CHEMBL314962 | cid_2822835 | N-Furan-2-ylmethyl-3,...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216265BDBM50216265(CHEMBL91526)
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216275BDBM50216275(CHEMBL315963)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216273BDBM50216273(CHEMBL88399)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216292BDBM50216292(CHEMBL89478)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216274BDBM50216274(CHEMBL88524)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50216262BDBM50216262(CHEMBL90278)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Rolipram binding to phosphodiesterase 4 at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216289BDBM50216289(CHEMBL88384)
Affinity DataIC50: 4.10E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216287BDBM50216287(CHEMBL313600)
Affinity DataIC50: 4.30E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216265BDBM50216265(CHEMBL91526)
Affinity DataIC50: 4.30E+3nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216275BDBM50216275(CHEMBL315963)
Affinity DataIC50: 4.50E+3nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216260BDBM50216260(CHEMBL313397)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216283BDBM50216283(CHEMBL328733)
Affinity DataIC50: 5.20E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216263BDBM50216263(CHEMBL313096)
Affinity DataIC50: 5.30E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216270BDBM50216270(CHEMBL315779)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216271BDBM50216271(CHEMBL92362)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216285BDBM50216285(CHEMBL328945)
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216288BDBM50216288(CHEMBL88699)
Affinity DataIC50: 7.80E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216261BDBM50216261(CHEMBL88775)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216266BDBM50216266(CHEMBL86946)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216268BDBM50216268(CHEMBL89513)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216281BDBM50216281(CHEMBL314122)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216267BDBM50216267(CHEMBL86997)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216274BDBM50216274(CHEMBL88524)
Affinity DataIC50: 1.10E+4nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50071804BDBM50071804(CHEMBL314962 | cid_2822835 | N-Furan-2-ylmethyl-3,...)
Affinity DataIC50: 1.50E+4nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216259BDBM50216259(CHEMBL430828)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216264BDBM50216264(CHEMBL327835)
Affinity DataIC50: 1.90E+4nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216282BDBM50216282(CHEMBL330581)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216292BDBM50216292(CHEMBL89478)
Affinity DataIC50: 2.40E+4nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216290BDBM50216290(CHEMBL88625)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216290BDBM50216290(CHEMBL88625)
Affinity DataIC50: 3.50E+4nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216259BDBM50216259(CHEMBL430828)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216271BDBM50216271(CHEMBL92362)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216286BDBM50216286(CHEMBL88119)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro binding activity towards catalytic site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50216264BDBM50216264(CHEMBL327835)
Affinity DataIC50: 1.12E+5nMAssay Description:Binding activity towards Rolipram binding site of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chiroscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of phosphodiesterase 5 at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed