Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50034965
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072257(2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50: 180nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072257(2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50: 180nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50061915(CHEMBL554000 | CHEMBL139909 | 2-Amino-4-(3,4-dichl...)
Affinity DataIC50: 200nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50061915(CHEMBL554000 | CHEMBL139909 | 2-Amino-4-(3,4-dichl...)
Affinity DataIC50: 200nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50061915(CHEMBL554000 | CHEMBL139909 | 2-Amino-4-(3,4-dichl...)
Affinity DataIC50: 330nMAssay Description:Compound was evaluated for the inhibition of rat liver KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072248((S)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyri...)
Affinity DataIC50: 420nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072244(4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-but-2-enoi...)
Affinity DataIC50: 440nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072249(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-butyric acid |...)
Affinity DataIC50: 480nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072245(4-(3,4-Dichloro-phenyl)-4-oxo-butyric acid | CHEMB...)
Affinity DataIC50: 900nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072254((E)-4-(3,4-Dichloro-phenyl)-4-oxo-but-2-enoic acid...)
Affinity DataIC50: 900nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50: 950nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072255((E)-4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072249(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-butyric acid |...)
Affinity DataIC50: 1.10E+3nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072250(4-(3,4-Dichloro-phenyl)-2-methoxy-4-oxo-butyric ac...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072244(4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-but-2-enoi...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was evaluated for inhibition of rat liver KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072252(4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072258(2-Hydroxy-4-(3-nitro-phenyl)-4-oxo-butyric acid | ...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072253(CHEMBL99588 | CHEMBL318692 | 4-(3,4-Dichloro-pheny...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072251(2-Chloro-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072259((S)-2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric...)
Affinity DataIC50: 2.30E+3nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072257(2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50: 2.90E+3nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072252(4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 3.30E+3nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072247(4-(3,4-Dichloro-phenyl)-2-methyl-4-oxo-butyric aci...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072245(4-(3,4-Dichloro-phenyl)-4-oxo-butyric acid | CHEMB...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072246(4-(3-Fluoro-phenyl)-2-hydroxy-4-oxo-butyric acid |...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50: 6.40E+3nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072250(4-(3,4-Dichloro-phenyl)-2-methoxy-4-oxo-butyric ac...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072247(4-(3,4-Dichloro-phenyl)-2-methyl-4-oxo-butyric aci...)
Affinity DataIC50: 6.90E+3nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072246(4-(3-Fluoro-phenyl)-2-hydroxy-4-oxo-butyric acid |...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072254((E)-4-(3,4-Dichloro-phenyl)-4-oxo-but-2-enoic acid...)
Affinity DataIC50: 1.04E+4nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072262((R)-2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric...)
Affinity DataIC50: 1.07E+4nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072253(CHEMBL99588 | CHEMBL318692 | 4-(3,4-Dichloro-pheny...)
Affinity DataIC50: 1.13E+4nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072258(2-Hydroxy-4-(3-nitro-phenyl)-4-oxo-butyric acid | ...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072261((R)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyri...)
Affinity DataIC50: 1.44E+4nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072251(2-Chloro-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072243(4-(3,4-Dichloro-phenyl)-4-oxo-2-phenyl-butyric aci...)
Affinity DataIC50: 1.95E+4nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072255((E)-4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid...)
Affinity DataIC50: 2.11E+4nMAssay Description:compound was evaluated for inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072253(CHEMBL99588 | CHEMBL318692 | 4-(3,4-Dichloro-pheny...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed