Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50048454
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215268BDBM50215268(CHEMBL325211)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067495BDBM50067495(2-(4-Fluoro-phenyl)-4-(3-methoxy-benzyloxy)-3-pyri...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215161BDBM50215161(CHEMBL324468)
Affinity DataIC50: 2nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215299BDBM50215299(CHEMBL263536)
Affinity DataIC50: 4nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215274BDBM50215274(CHEMBL332917)
Affinity DataIC50: 6nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215267BDBM50215267(RWJ-68354 | CHEMBL115769)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215158BDBM50215158(CHEMBL333823)
Affinity DataIC50: 9nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215272BDBM50215272(CHEMBL115778)
Affinity DataIC50: 9nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215154BDBM50215154(CHEMBL112691)
Affinity DataIC50: 15nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045333BDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: 25nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215159BDBM50215159(CHEMBL112274)
Affinity DataIC50: 30nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215262BDBM50215262(CHEMBL112273)
Affinity DataIC50: 37nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215160BDBM50215160(CHEMBL320255)
Affinity DataIC50: 40nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215263BDBM50215263(CHEMBL114525)
Affinity DataIC50: 60nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215266BDBM50215266(CHEMBL322770)
Affinity DataIC50: 100nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215265BDBM50215265(CHEMBL112396)
Affinity DataIC50: 100nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215273BDBM50215273(CHEMBL113013)
Affinity DataIC50: 125nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215264BDBM50215264(CHEMBL263280)
Affinity DataIC50: 200nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215271BDBM50215271(CHEMBL410857)
Affinity DataIC50: 200nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215155BDBM50215155(CHEMBL321196)
Affinity DataIC50: 300nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215270BDBM50215270(CHEMBL326584)
Affinity DataIC50: 300nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215275BDBM50215275(CHEMBL321851)
Affinity DataIC50: 400nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215157BDBM50215157(CHEMBL321879)
Affinity DataIC50: 400nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215261BDBM50215261(CHEMBL326122)
Affinity DataIC50: 400nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215156BDBM50215156(CHEMBL326923)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215300BDBM50215300(CHEMBL112036)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215269BDBM50215269(CHEMBL321148)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2018
Entry Details Article
PubMed