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Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 3456
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400811BDBM400811(US10000487, Example 2F)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400832BDBM400832(6'-((2H-1,2,3-triazol-4-yl)amino)-8'-chloro-2'H-sp...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400834BDBM400834(6'-((1,3,5-triazin-2-yl)amino)-8'-chloro-2'H-spiro...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400829BDBM400829(6'-((1,2,5-thiadiazol-3-yl)amino)-8'-chloro-2'H-sp...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400830BDBM400830(8'-chloro-6'-((2-methyl-2H-1,2,3-triazol-4-yl)amin...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400811BDBM400811(US10000487, Example 2F)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400835BDBM400835(6'-((1,2,4-triazin-3-yl)amino)-8'-chloro-2'H-spiro...)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400836BDBM400836(6'-((2-aminopyridin-4-yl)amino)-8'-chloro-2'H-spir...)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400826BDBM400826(6'-((1,2,3-thiadiazol-5-yl)amino)-8'-chloro-2'H-sp...)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400832BDBM400832(6'-((2H-1,2,3-triazol-4-yl)amino)-8'-chloro-2'H-sp...)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400833BDBM400833(6'-((1,2,4-triazin-3-yl)amino)-8'-chloro-2'H-spiro...)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400805BDBM400805(US10000487, Example 1F)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400827BDBM400827(US10000487, Example 4F)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400828BDBM400828(8'-chloro-6'-(thiazol-5-ylamino)-2'H-spiro[cyclohe...)
Affinity DataIC50: 55nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400805BDBM400805(US10000487, Example 1F)
Affinity DataIC50: 5.05E+3nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400831BDBM400831(6'-((1,3,4-oxadiazol-2-yl)amino)-8'-chloro-2'H-spi...)
Affinity DataIC50: 5.05E+3nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400831BDBM400831(6'-((1,3,4-oxadiazol-2-yl)amino)-8'-chloro-2'H-spi...)
Affinity DataIC50: 5.05E+3nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400827BDBM400827(US10000487, Example 4F)
Affinity DataIC50: 5.05E+3nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400828BDBM400828(8'-chloro-6'-(thiazol-5-ylamino)-2'H-spiro[cyclohe...)
Affinity DataIC50: 5.05E+3nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400835BDBM400835(6'-((1,2,4-triazin-3-yl)amino)-8'-chloro-2'H-spiro...)
Affinity DataIC50: 1.00E+7nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 400826BDBM400826(6'-((1,2,3-thiadiazol-5-yl)amino)-8'-chloro-2'H-sp...)
Affinity DataIC50: 1.00E+7nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent