Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 217
TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228251BDBM228251(US10047084, 34 | N-((1s,4s)-4-(3-methyl-8-(6-(1-me...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228206BDBM228206(US10047084, 5 | 1-(1-((R)-2-hydroxypropionyl)piper...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228250BDBM228250(US10047084, 33 | N-((1s,4s)-4-(3-methyl-8-(6-(1-me...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228226BDBM228226(US10047084, 18 | 1-((1s,4s)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228204BDBM228204(US10047084, 3 | US10047084, 36 | 3-methyl-8-(6-(1-...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228248BDBM228248(US10047084, 31 | (R)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228245BDBM228245(US10047084, 28 | (S)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228226BDBM228226(US10047084, 18 | 1-((1s,4s)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228243BDBM228243(US10047084, 27 | (R)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228242BDBM228242(US10047084, 26 | 8-(6-aminopyridin-3-yl)1-((1s,4s)...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228253BDBM228253(US10047084, 35 | (1s,4s)-4-(3-methyl-8-(6-(1-methy...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228204BDBM228204(US10047084, 3 | US10047084, 36 | 3-methyl-8-(6-(1-...)
Affinity DataIC50: 10nMAssay Description:PI3K alpha-ADP Glo Assay was employed. In the determination of PI3K enzyme activity, the detection kit supplied by Promega (Promega, Cat #: V9101) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228207BDBM228207(US10047084, 6 | 3-methyl-8-(6-(1-methyl-1H-pyrazol...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228223BDBM228223(US10047084, 17 | 1-((1r,4r)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228257BDBM228257(US10047084, 39 | (S)-3-methyl-1-(1-(methanesulfony...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228246BDBM228246(US10047084, 29 | (S)-1-(1-(ethylsulfonyl)pyrrolidi...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228256BDBM228256(US10047084, 38 | (S)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228255BDBM228255(US10047084, 37 | 3-methyl-8-(6-(1-methyl-1H-pyrazo...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228245BDBM228245(US10047084, 28 | (S)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228227BDBM228227(US10047084, 19 | 1-((1s,4s)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228249BDBM228249(US10047084, 32 | 1-(3-hydroxycyclohexyl)-3-methyl-...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228204BDBM228204(US10047084, 3 | US10047084, 36 | 3-methyl-8-(6-(1-...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228248BDBM228248(US10047084, 31 | (R)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228247BDBM228247(US10047084, 30 | (S)-3-methyl-1-(1-(methanesulfony...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228236BDBM228236(US10047084, 25 | 1-((1r,4r)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 25nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228229BDBM228229(US10047084, 20 | 1-((1s,4s)-4-hydroxycyclohexyl)-8...)
Affinity DataIC50: 55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228235BDBM228235(US10047084, 24 | 1-((1r,4r)-4-hydroxycyclohexyl)-8...)
Affinity DataIC50: 55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228205BDBM228205(US10047084, 4 | 1-(1-((S)-2-hydroxypropionyl)piper...)
Affinity DataIC50: 55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228234BDBM228234(US10047084, 23 | 1-((1r,4r)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228233BDBM228233(US10047084, 22 | 1-((1s,4s)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228200BDBM228200(US10047084, 1 | 1-(1-(2-hydroxyacetyl)piperidin-3-...)
Affinity DataIC50: 55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228232BDBM228232(US10047084, 21 | 1-((1s,4s)-4-hydroxycyclohexyl)-3...)
Affinity DataIC50: 55nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228215BDBM228215(US10047084, 11 | 1-(1-acetylpyrrolidin-3-yl)-3-met...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228222BDBM228222(US10047084, 16 | 3-methyl-8-(6-(1-methyl-1H-pyrazo...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228221BDBM228221(US10047084, 15 | 3-(3-methyl-8-(6-(1-methyl-1H-pyr...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228212BDBM228212(US10047084, 10 | 1-(1-ethylpyrrolidin-3-yl)-3-meth...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228220BDBM228220(US10047084, 14 | 3-methyl-8-(6-(1-methyl-1H-pyrazo...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228210BDBM228210(US10047084, 9 | 3-methyl-8-(6-(1-methyl-1H-pyrazol...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228243BDBM228243(US10047084, 27 | (R)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228209BDBM228209(US10047084, 7 | 1-(1-(2-hydroxyacetyl)pyrrolidin-3...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228217BDBM228217(US10047084, 13 | 1-(1-((4-chlorphenyl)sulfonyl)pyr...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228203BDBM228203(US10047084, 2 | 1-(1-(1H-1,2,4-triazole-3-carbonyl...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228216BDBM228216(US10047084, 12 | 1-(1-benzylpyrrolidin-3-yl)-3-met...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent