Compile Data Set for Download or QSAR
Report error Found 375 Enz. Inhib. hit(s) with all data for entry = 236
TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243413BDBM243413(5-((1R,2R)-2-((4,4- difluorocyclohexyl)- amino)cyc...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256707BDBM256707(US9487511, 89 | US10053456, 89 | US9718814, 89 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243411BDBM243411(US9718814, 46 | 5-((1R,2R)-2-(cis- (4-aminocyclohe...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256706BDBM256706(US9487511, 88 | US10053456, 88 | US9718814, 88 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243411BDBM243411(US9718814, 46 | 5-((1R,2R)-2-(cis- (4-aminocyclohe...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 244007BDBM244007(5-((1R,2R)-2-((1- (cyclopropyl- carbonyl)piperidin...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243415BDBM243415(N-(5-methyl-1,3,4- thiadiazol-2-yl)-5- ((1R,2R)-2-...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 244006BDBM244006(5-((1R,2R)-2-((1- acetylpiperidin-4- yl)amino)cycl...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243414BDBM243414(5-((1R,2R)-2-((1- cyclopropylpiperi- din-4-yl)amin...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256708BDBM256708(US9487511, 90 | US10053456, 90 | US9718814, 90 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243418BDBM243418(5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243417BDBM243417(N-(4,4- difluorocyclohexyl)- 5-((1R,2R)-2- ((tetra...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243416BDBM243416(N-(2-methyl-1,3- thiazol-5-yl)-5- ((1R,2R)-2- (tet...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243421BDBM243421(N-(1,5-dimethyl-1H- pyrazol-4-yl)-5- ((1R,2R)-2- (...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256633BDBM256633(US9487511, 12 | US10053456, 12 | US9718814, 12 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50153590BDBM50153590(US9487511, 97 | CHEMBL3774809 | US10053456, 97 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243420BDBM243420(N-(1,3-dimethyl-1H- pyrazol-4-yl)-5- ((1R,2R)-2- (...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243419BDBM243419(N-(2-methyl-1,3- thiazol-5-yl)-5- ((1R,2R)-2- ((te...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50153591BDBM50153591(US9487511, 99 | CHEMBL3775711 | US10053456, 99 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256677BDBM256677(US9487511, 56 | US10053456, 56 | US9718814, 56 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243426BDBM243426(3-(4-((((1R,2R)-2- (4-((5-methyl-1,3,4- thiadiazol...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256680BDBM256680(US9487511, 59 | US10053456, 59 | US9718814, 59 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256637BDBM256637(US9487511, 16 | US10053456, 16 | US9718814, 16 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 244016BDBM244016(4-((4-((((1R,2R)-2- (4-((4,4-difluoro- cyclohexyl)...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256679BDBM256679(US9487511, 58 | US10053456, 58 | US9718814, 58 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256641BDBM256641(US9487511, 20 | US10053456, 20 | US9718814, 20 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256683BDBM256683(US9487511, 62 | US10053456, 62 | US9718814, 62 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50153593BDBM50153593(US9487511, 123 | CHEMBL3775351 | US10053456, 123 |...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 243427BDBM243427(4-(trans-2- (cyclobutylamino)- cyclopropyl)-N-(1- ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256644BDBM256644(US9487511, 23 | US10053456, 23 | US9718814, 23 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256686BDBM256686(US9487511, 65 | US10053456, 65 | US9718814, 65 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256724BDBM256724(US9487511, 111 | US10053456, 111 | US9718814, 111 ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256723BDBM256723(US9487511, 110 | US10053456, 110 | US9718814, 110 ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256688BDBM256688(US9487511, 67 | US10053456, 67 | US9718814, 67 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256645BDBM256645(US9487511, 24 | US10053456, 24 | US9718814, 24 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256687BDBM256687(US9487511, 66 | US10053456, 66 | US9718814, 66 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50153586BDBM50153586(CHEMBL3775474 | US10053456, 120 | US9718814, 71 | ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256649BDBM256649(US9487511, 28 | US10053456, 28 | US9718814, 28 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50153586BDBM50153586(CHEMBL3775474 | US10053456, 120 | US9718814, 71 | ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256691BDBM256691(US9487511, 70 | US10053456, 70 | US9718814, 70 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 244027BDBM244027(5-((1R,2R)-2- ((cyclobutylmethyl)- amino)cycloprop...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256690BDBM256690(US9487511, 69 | US10053456, 69 | US9718814, 69 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256652BDBM256652(US9487511, 31 | US10053456, 31 | US9718814, 31 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256651BDBM256651(US9487511, 30 | US10053456, 30 | US9718814, 30 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50153586BDBM50153586(CHEMBL3775474 | US10053456, 120 | US9718814, 71 | ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256692BDBM256692(US9487511, 72 | US10053456, 72 | US9718814, 72 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50153586BDBM50153586(CHEMBL3775474 | US10053456, 120 | US9718814, 71 | ...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256654BDBM256654(US9487511, 33 | US10053456, 33 | US9718814, 33 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256653BDBM256653(US9487511, 32 | US10053456, 32 | US9718814, 32 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256694BDBM256694(US9487511, 74 | US10053456, 74 | US9718814, 74 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

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