Compile Data Set for Download or QSAR
Report error Found 195 Enz. Inhib. hit(s) with all data for entry = 240
TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174787BDBM174787(US9102686, 18 | US9540388, 18 | US10053462, 18)
Affinity DataIC50: 1.10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174777BDBM174777(US9102686, 8 | US9540388, 8 | US10053462, 8)
Affinity DataKi:  1.30nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174795BDBM174795(US9102686, 26 | US9540388, 26 | US10053462, 26)
Affinity DataIC50: 1.40nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203318BDBM203318(US10053462, 196 | US9540388, 196 | (6r,10s)-11-{[2...)
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174827BDBM174827(US9102686, 58 | US9540388, 58 | US10053462, 58)
Affinity DataIC50: 1.70nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203318BDBM203318(US10053462, 196 | US9540388, 196 | (6r,10s)-11-{[2...)
Affinity DataIC50: 1.70nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203334BDBM203334(US10053462, 203 | US9540388, 203 | (6r,10s)-11-[(2...)
Affinity DataKi:  2.20nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174777BDBM174777(US9102686, 8 | US9540388, 8 | US10053462, 8)
Affinity DataIC50: 2.5nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174830BDBM174830(US9102686, 61 | US9540388, 61 | US10053462, 61)
Affinity DataIC50: 2.60nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174822BDBM174822(US9102686, 53 | US9540388, 53 | US10053462, 53)
Affinity DataIC50: 3.10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203315BDBM203315(US10053462, 194 | US9540388, 194 | (6r,10s)-11-{[2...)
Affinity DataKi:  3.10nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174802BDBM174802(US9102686, 33 | US9540388, 32 | US10053462, 33)
Affinity DataKi:  3.20nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203332BDBM203332(US10053462, 201 | US9540388, 201 | (6r,10s)-11-{[2...)
Affinity DataKi:  3.20nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203331BDBM203331(US10053462, 200 | US9540388, 200 | (6r,10s)-11-{[2...)
Affinity DataKi:  3.20nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174781BDBM174781(US9102686, 12 | US9540388, 12 | US10053462, 12)
Affinity DataKi:  3.40nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174770BDBM174770(US9102686, 1 | US9540388, 1 | US10053462, 1)
Affinity DataIC50: 3.80nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203333BDBM203333(US10053462, 202 | US9540388, 202 | (6r,10s)-11-[(2...)
Affinity DataKi:  3.90nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174818BDBM174818(US9102686, 49 | US9540388, 49 | US10053462, 49)
Affinity DataKi:  4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174772BDBM174772(US9102686, 3 | US9540388, 3 | US10053462, 3)
Affinity DataKi:  4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174830BDBM174830(US9102686, 61 | US9540388, 61 | US10053462, 61)
Affinity DataKi:  4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174795BDBM174795(US9102686, 26 | US9540388, 26 | US10053462, 26)
Affinity DataKi:  4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174787BDBM174787(US9102686, 18 | US9540388, 18 | US10053462, 18)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174770BDBM174770(US9102686, 1 | US9540388, 1 | US10053462, 1)
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203314BDBM203314(US10053462, 193 | US9540388, 193 | (6r,10s)-11-{[2...)
Affinity DataKi:  4.90nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203324BDBM203324(US10053462, 199 | US9540388, 199 | (6r,10s)-11-{[3...)
Affinity DataKi:  5nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174792BDBM174792(US9102686, 23 | US9540388, 23 | US10053462, 23)
Affinity DataKi:  5nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174818BDBM174818(US9102686, 49 | US9540388, 49 | US10053462, 49)
Affinity DataIC50: 5nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203334BDBM203334(US10053462, 203 | US9540388, 203 | (6r,10s)-11-[(2...)
Affinity DataKi:  5.30nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203333BDBM203333(US10053462, 202 | US9540388, 202 | (6r,10s)-11-[(2...)
Affinity DataKi:  5.80nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203318BDBM203318(US10053462, 196 | US9540388, 196 | (6r,10s)-11-{[2...)
Affinity DataKi:  5.80nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174823BDBM174823(US9102686, 54 | US9540388, 54 | US10053462, 54)
Affinity DataIC50: 6.10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203323BDBM203323(US10053462, 198 | US9540388, 198 | (6r,10s)-11-{[3...)
Affinity DataKi:  6.20nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174815BDBM174815(US9102686, 46 | US9540388, 46 | US10053462, 46)
Affinity DataKi:  6.30nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174810BDBM174810(US9102686, 41 | US9540388, 41 | US10053462, 41)
Affinity DataIC50: 6.30nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174831BDBM174831(US9102686, 62 | US9540388, 62 | US10053462, 62)
Affinity DataKi:  6.30nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174821BDBM174821(US9102686, 52 | US9540388, 52 | US10053462, 52)
Affinity DataKi:  6.30nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174816BDBM174816(US9102686, 47 | US9540388, 47 | US10053462, 47)
Affinity DataKi:  6.30nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203315BDBM203315(US10053462, 194 | US9540388, 194 | (6r,10s)-11-{[2...)
Affinity DataIC50: 7.40nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174813BDBM174813(US9102686, 44 | US9540388, 44 | US10053462, 44)
Affinity DataIC50: 7.70nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174776BDBM174776(US9102686, 7 | US9540388, 7 | US10053462, 7)
Affinity DataIC50: 7.70nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174811BDBM174811(US9102686, 42 | US9540388, 42 | US10053462, 42)
Affinity DataKi:  7.90nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174823BDBM174823(US9102686, 54 | US9540388, 54 | US10053462, 54)
Affinity DataKi:  7.90nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174810BDBM174810(US9102686, 41 | US9540388, 41 | US10053462, 41)
Affinity DataKi:  7.90nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174822BDBM174822(US9102686, 53 | US9540388, 53 | US10053462, 53)
Affinity DataKi:  7.90nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174820BDBM174820(US9102686, 51 | US9540388, 51 | US10053462, 51)
Affinity DataKi:  7.90nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174772BDBM174772(US9102686, 3 | US9540388, 3 | US10053462, 3)
Affinity DataIC50: 8.10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174783BDBM174783(US9102686, 14 | US9540388, 14 | US10053462, 14)
Affinity DataIC50: 8.20nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174772BDBM174772(US9102686, 3 | US9540388, 3 | US10053462, 3)
Affinity DataIC50: 9.60nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 174777BDBM174777(US9102686, 8 | US9540388, 8 | US10053462, 8)
Affinity DataIC50: 9.70nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 203323BDBM203323(US10053462, 198 | US9540388, 198 | (6r,10s)-11-{[3...)
Affinity DataKi:  9.80nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

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