Compile Data Set for Download or QSAR
Report error Found 230 Enz. Inhib. hit(s) with all data for entry = 446
TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269453BDBM269453((E)-3-(4-((2-(5-fluoro- 2-(2,2,2- trifluoroethyl)p...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269484BDBM269484(US10058534, 139)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269433BDBM269433((E)-3-(4-((2-(4-fluoro- 2-(2,2,2- trifluoroethyl)p...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269431BDBM269431((E)-3-(4-((2-(2-(sec- butyl)phenyl)-6- hydroxybenz...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269467BDBM269467((E)-3-(4-((2-(2-(1,1- difluoroethyl)phenyl)-6- hyd...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269446BDBM269446((E)-3-(4-((7-fluoro-6- hydroxy-2-(2- isopropylphen...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269454BDBM269454((E)-3-(4-((6-hydroxy-2- (2-(2,2,2- trifluoroethyl)...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269456BDBM269456((E)-3-(4-((2-(2-(1- fluoroethyl)phenyl)-6- hydroxy...)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269432BDBM269432((E)-3-(4-((2-(2- cyclopentylphenyl)-6- hydroxybenz...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269308BDBM269308((E)-3-(4-((6-hydroxy-2- (2-isopropylphenyl)- benzo...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269434BDBM269434((E)-3-(4-((2-(2- cyclobutylphenyl)-6- hydroxybenzo...)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269455BDBM269455((E)-3-(4-((2-(4-fluoro- 2-isopropylphenyl)-6- hydr...)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269457BDBM269457((E)-3-(4-((6-hydroxy-2- (2- (trifluoromethoxy)phen...)
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269447BDBM269447((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-methyl-1,3,...)
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269357BDBM269357((E)-3-(4-((2-(2,4- bis(trifluoromethyl) phenyl)-6-...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269364BDBM269364((E)-3-(4-((2-(2- ethylphenyl)-6- hydroxybenzo[b] t...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269363BDBM269363((E)-3-(4-((2-(4-fluoro- 2-(trifluoromethyl)- pheny...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269354BDBM269354((E)-3-(4-((6-hydroxy-2- (2-(trifluoromethyl)- phen...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269377BDBM269377(US10058534, 31)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269399BDBM269399(US10058534, 54)
Affinity DataIC50: 1nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269366BDBM269366((E)-3-(4-((2-(2-(tert- butyl)phenyl)-6- hydroxyben...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269468BDBM269468((E)-3-(4-((6-hydroxy-2- (2-(oxetan-3- yl)phenyl)be...)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269450BDBM269450((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-methyl-4H-1...)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269447BDBM269447((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-methyl-1,3,...)
Affinity DataIC50: 1.20nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269435BDBM269435((E)-3-(4-((2-(3-fluoro- 2- (trifluoromethyl) pheny...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269422BDBM269422((E)-3-(4-((2-(2- ((dimethylamino)methyl) phenyl)-6...)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269469BDBM269469((E)-3-(4-((6-hydroxy-2- (2-isopropyl-6- methylphen...)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269438BDBM269438(3-(4-((6-hydroxy-2-(2- isopropylphenyl)benzo [b]th...)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269441BDBM269441((E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol...)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269440BDBM269440((E)-3-(4-((2-(5-fluoro- 2- (trifluoromethyl) pheny...)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269359BDBM269359((E)-3-(4-((2-(2,3- dimethylphenyl)-6- hydroxybenzo...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269458BDBM269458((E)-2-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo ...)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269463BDBM269463((E)-3-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo ...)
Affinity DataIC50: 2.80nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269400BDBM269400((E)-2-(4- hydroxyphenyl)-3-(4- (2-(2-methyl-2H- te...)
Affinity DataIC50: 3nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269425BDBM269425(US10058534, 80)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269448BDBM269448((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-1,3,...)
Affinity DataIC50: 3.30nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269452BDBM269452((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-4H-1...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269320BDBM269320((E)-3-(4-((6-hydroxy-2- (o-tolyl)benzo- [b]thiophe...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269358BDBM269358((E)-3-(4-((2-(4-fluoro- 2-methylphenyl)-6- hydroxy...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269451BDBM269451((E)-3-(4-(2-(4,5- dimethyl-4H-1,2,4- triazol-3- yl...)
Affinity DataIC50: 4.10nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269424BDBM269424(US10058534, 79)
Affinity DataIC50: 4.20nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269446BDBM269446((E)-3-(4-((7-fluoro-6- hydroxy-2-(2- isopropylphen...)
Affinity DataIC50: 4.20nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269472BDBM269472((E)-3-(4-((2-(2- cyclopropylphenyl)-6- hydroxybenz...)
Affinity DataIC50: 4.20nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269356BDBM269356((E)-3-(4-((6-hydroxy-2- (2-methyl-4- (trifluoromet...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269391BDBM269391(US10058534, 46)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269481BDBM269481((E)-3-(4-((2-(2- isopropylphenyl)-6- (propionyloxy...)
Affinity DataIC50: 5.10nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269465BDBM269465((E)-4-(4-((2-(4-fluoro- 2- (trifluoromethyl) pheny...)
Affinity DataIC50: 5.10nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269475BDBM269475((E)-3-(4-((2-(2,6- diethylphenyl)-6- hydroxybenzo[...)
Affinity DataIC50: 5.10nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269460BDBM269460((E)-3-(4-((6-hydroxy-2- (4-isopropyloxazol-5- yl)b...)
Affinity DataIC50: 5.30nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269445BDBM269445((E)-3-(4-((6-hydroxy-2- (2-methylpyridin-3- yl)ben...)
Affinity DataIC50: 5.40nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

Displayed 1 to 50 (of 230 total ) | Next | Last >>
Jump to: