Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 645
TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285498BDBM285498(US10077247, Example 18-1 | 4-[4-Cyano-2-({[(1R,2R)...)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285464BDBM285464(US10077247, Example 2-5 | 4-{4-Cyano-2-[({2′...)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285502BDBM285502(US10077247, Example 20-2)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285487BDBM285487(US10077247, Example 7-4 | 4-[4-Cyano-2-({[(2′...)
Affinity DataIC50: 2.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285036BDBM285036(US10077247, Example 1)
Affinity DataIC50: 2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285480BDBM285480(US10077247, Example 2-44 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285470BDBM285470(US10077247, Example 2-29 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285483BDBM285483(US10077247, Example 3 | 4-[4-Cyano-2-({[(2′R...)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285500BDBM285500(US10077247, Example 18-3 | 4-{4-Cyano-2-[({(1R,2R)...)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285484BDBM285484(US10077247, Example 5)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285482BDBM285482(US10077247, Example 2-46 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 3nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285499BDBM285499(US10077247, Example 18-2 | 4-{4-Cyano-2-[({(1R,2R)...)
Affinity DataIC50: 3nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285463BDBM285463(US10077247, Example 2-4)
Affinity DataIC50: 3.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285474BDBM285474(US10077247, Example 2-37 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285476BDBM285476(US10077247, Example 2-39)
Affinity DataIC50: 3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285478BDBM285478(US10077247, Example 2-41 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285462BDBM285462(US10077247, Example 2-3)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285495BDBM285495(US10077247, Example 10-4 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285489BDBM285489(US10077247, Example 7-13 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285479BDBM285479(US10077247, Example 2-43 | 4-{4-Cyano-2-[({(2̸...)
Affinity DataIC50: 3.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285471BDBM285471(US10077247, Example 2-32 | 4-{4-Cyano-2-[({(2̸...)
Affinity DataIC50: 3.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285486BDBM285486(US10077247, Example 7-3 | 4-[4-Cyano-2-({[(2′...)
Affinity DataIC50: 3.80nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285466BDBM285466(US10077247, Example 2-10 | 4-[4-cyano-2-({[(2̸...)
Affinity DataIC50: 4nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285496BDBM285496(US10077247, Example 10-5 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 4.10nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285512BDBM285512(US10077247, Example 38-2 | 4-[4-Cyano-2-({[(1S,2R)...)
Affinity DataIC50: 4.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285492BDBM285492(US10077247, Example 7-19 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285508BDBM285508(US10077247, Example 36 | 4-[4-Cyano-2-({[(2′...)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285465BDBM285465(US10077247, Example 2-9 | 4-{4-Cyano-2-[({(2′...)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285468BDBM285468(US10077247, Example 2-14 | 4-[4 Cyano 2-({[(2̸...)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285469BDBM285469(US10077247, Example 2-23 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285475BDBM285475(US10077247, Example 2-38)
Affinity DataIC50: 4.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285461BDBM285461(US10077247, Example 2-2)
Affinity DataIC50: 5.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285511BDBM285511(US10077247, Example 38-1 | 4-[4-Cyano-2-({[(1S,2R)...)
Affinity DataIC50: 5.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285473BDBM285473(US10077247, Example 2-36 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 5.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285490BDBM285490(US10077247, Example 7-16 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285494BDBM285494(US10077247, Example 10-3 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285513BDBM285513(US10077247, Example 39 | 4-[4-Cyano-2-({[(1S,2R)-3...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285491BDBM285491(US10077247, Example 7-17 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 6.10nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285510BDBM285510(US10077247, Example 37-2 | 4-{4-Cyano-2-[({(2̸...)
Affinity DataIC50: 6.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285504BDBM285504(US10077247, Example 28-1 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 6.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285497BDBM285497(US10077247, Example 10-9 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 6.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285505BDBM285505(US10077247, Example 28-2 | 4-{4-Cyano-2-[({(2̸...)
Affinity DataIC50: 6.90nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285509BDBM285509(US10077247, Example 37-1 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 7.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285477BDBM285477(US10077247, Example 2-40 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 7.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285467BDBM285467(US10077247, Example 2-13 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 7.80nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285481BDBM285481(US10077247, Example 2-45 | 4-{4-Cyano-2-[({(2̸...)
Affinity DataIC50: 8.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285507BDBM285507(US10077247, Example 33-2 | 4-{4-Cyano-2-[({(2̸...)
Affinity DataIC50: 8.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285501BDBM285501(US10077247, Example 20-1 | 4-[4-Cyano-2-(({[(2R...)
Affinity DataIC50: 8.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285488BDBM285488(US10077247, Example 7-10 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 8.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 285503BDBM285503(US10077247, Example 20-5 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 9.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

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