Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 884
TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296836BDBM296836(US10112944, Example 10 | US10112944, Example 29 | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296838BDBM296838(1-(2,5-Dimethylphenyl)-8-(1-methyl-1H-pyrazol-4-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296839BDBM296839(1-(2-(Difluoromethoxy)phenyl)-8-(1-methyl-1H-pyraz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296840BDBM296840(4-(5-(1-(2,5-Dimethylphenyl)-1,2,3,4-tetrahydroimi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296841BDBM296841(4-(5-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296842BDBM296842(2-(4-(1-(2,5-Dimethylphenyl)-1,2,3,4-tetrahydroimi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296843BDBM296843(2-(4-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296828BDBM296828(1-(2-(Difluoromethoxy)phenyl)-8-(6-methoxypyridin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296829BDBM296829(1-(2,5-Dimethylphenyl)-7-methyl-8-(1-methyl-1H-pyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296831BDBM296831(1-(2,5-Dimethylphenyl)-8-(6-methoxypyridin-3-yl)-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296832BDBM296832(1-(2-(Difluoromethoxy)phenyl)-8-(6-methoxypyridin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296833BDBM296833(US10112944, Example 7 | US10112944, Example 27 | 1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296835BDBM296835(8-(6-Methoxypyridin-3-yl)-1-(o-tolyl)-1,2,3,4-tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296852BDBM296852(1-(4-Fluoro-2-methylphenyl)-8-(6-methoxypyridin-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296833BDBM296833(US10112944, Example 7 | US10112944, Example 27 | 1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296854BDBM296854(1-(2-Ethylphenyl)-8-(6-methoxypyridin-3-yl)-1,2,3,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296836BDBM296836(US10112944, Example 10 | US10112944, Example 29 | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296857BDBM296857(1-(2-Chlorophenyl)-8-(6-methoxypyridin-3-yl)-1,2,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296858BDBM296858(1-(5-Chloro-2-methylphenyl)-8-(6-methoxypyridin-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296840BDBM296840(4-(5-(1-(2,5-Dimethylphenyl)-1,2,3,4-tetrahydroimi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296844BDBM296844(2-(5-(1-(2,5-Dimethylphenyl)-1,2,3,4-tetrahydroimi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296845BDBM296845(4-(5-(1-(2-(Difluoromethoxy)-5-methylphenyl)-1,2,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296846BDBM296846(1-(2-(Difluoromethoxy)-5-methylphenyl)-8-(6-methox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296847BDBM296847(2-(5-(7-Chloro-1-phenyl-1,2,3,4-tetrahydroimidazo[...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296851BDBM296851(1-(5-Fluoro-2-methylphenyl)-8-(6-methoxypyridin-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296860BDBM296860(2-(5-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296861BDBM296861(2-(4-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296863BDBM296863(1-(2,5-Dimethylphenyl)-8-(6-methoxypyridin-3-yl)-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296864BDBM296864(1-(2-(Difluoromethoxy)phenyl)-8-(6-methoxypyridin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296838BDBM296838(1-(2,5-Dimethylphenyl)-8-(1-methyl-1H-pyrazol-4-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296866BDBM296866(1-(2-(Difluoromethoxy)phenyl)-4-methyl-8-(1-methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296837BDBM296837(8-(6-Methoxypyridin-3-yl)-1-(2-methyl-5-(trifluoro...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296856BDBM296856(1-(2,4-Dimethylphenyl)-8-(6-methoxypyridin-3-yl)-1...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296827BDBM296827(1-(2,5-Dimethylphenyl)-8-(6-methoxypyridin-3-yl)-7...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296830BDBM296830(1-(2-(Difluoromethoxy)phenyl)-7-methyl-8-(1-methyl...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296862BDBM296862(2-(4-(1-(2,5-Dimethylphenyl)-1,2,3,4-tetrahydroimi...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296848BDBM296848(7-Chloro-1-(2-(difluoromethoxy)phenyl)-8-(6-methox...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296849BDBM296849(7-Chloro-1-(2,5-dimethylphenyl)-8-(6-methoxypyridi...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296834BDBM296834(1-(Isoquinolin-1-yl)-8-(6-methoxypyridin-3-yl)-1,2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296850BDBM296850(1-(2,3-Dimethylphenyl)-8-(6-methoxypyridin-3-yl)-1...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296867BDBM296867(4-(5-(1-(2,5-Dimethylphenyl)-6,7-dimethyl-1,2,3,4-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent