Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 912
TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298291BDBM298291(US10123984, Example 2N | US11547687, Example 2N | ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298292BDBM298292(US10123984, Example 2T | US10744104, Example 2T | ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298293BDBM298293(US11547687, Example 2U | US10744104, Example 2U | ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298294BDBM298294(US11547687, Example 2V | US10744104, Example 2V | ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298295BDBM298295(US20230285340, Example 3A | US10123984, Example 3D...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298295BDBM298295(US20230285340, Example 3A | US10123984, Example 3D...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298317BDBM298317(US10123984, Example 11-2)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298285BDBM298285(US11547687, Example 2A | US11547687, Compound Exam...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298286BDBM298286(US11547687, Example 2F | US10744104, Example 2F | ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298288BDBM298288(US11547687, Example 2H | US10123984, Example 2H | ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298322BDBM298322(US10123984, Example 14A | US10123984, Example 14F ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298305BDBM298305(US11547687, Compound Example 5A | US10123984, Exam...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298306BDBM298306(US10123984, Example 7B | US11547687, Example 7B)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298307BDBM298307(US10123984, Example 8-2 | US10744104, Example 8-2 ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298308BDBM298308(US10123984, Example 8-3 | US10744104, Example 8-3 ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298298BDBM298298(US10123984, Example 5-1)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298299BDBM298299(US10123984, Example 5-5)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298300BDBM298300(US10123984, Example 5-9 | US20230285340, Example 5...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298301BDBM298301(US10123984, Example 5-13 | US20230285340, Example ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298302BDBM298302(US10123984, Example 5-14)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298303BDBM298303(US10123984, Example 5-15)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298304BDBM298304(US10123984, Example 5-17 | US20230285340, Example ...)
Affinity DataKi: <1nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298289BDBM298289(US10744104, Example 2I | US11547687, Example 2I | ...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298322BDBM298322(US10123984, Example 14A | US10123984, Example 14F ...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298322BDBM298322(US10123984, Example 14A | US10123984, Example 14F ...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298326BDBM298326(US10123984, Example 16 | US10744104, Example 16 | ...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298315BDBM298315(US11547687, Example 11-1 | US10744104, Example 10 ...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298316BDBM298316(US10123984, Example 11-1 | US10744104, Example 11-...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298319BDBM298319(US10123984, Example 11-4 | US10744104, Example 11-...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298287BDBM298287(US11547687, Example 2G | US10744104, Example 2G | ...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298321BDBM298321(US10123984, Example 13 | (R)-3-[N-(3′-Chloro...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298309BDBM298309(US10123984, Example 8-4 | US20230285340, Example 8...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298310BDBM298310(US10123984, Example 8-5)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298312BDBM298312(US10123984, Example 9A | US10744104, Example 9A | ...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298297BDBM298297(US10123984, Example 4 | (2R,4R)-5-(3-Chlorobipheny...)
Affinity DataKi:  3.55nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 50034842BDBM50034842((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...)
Affinity DataIC50: 5nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298327BDBM298327(US10123984, Comparative Compound A )
Affinity DataKi:  6.31nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298328BDBM298328(US10123984, Comparative Compound B)
Affinity DataKi:  6.31nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 50034846BDBM50034846((2R,4R)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...)
Affinity DataIC50: 27nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298290BDBM298290(US10744104, Example 2J | US10123984, Example 2J | ...)
Affinity DataKi:  35.5nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298325BDBM298325(US10123984, Example 15 | (2R,4S)-5-Biphenyl-4-yl-2...)
Affinity DataKi:  35.5nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298311BDBM298311(US10123984, Example 8-6)
Affinity DataKi:  35.5nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298284BDBM298284(US10123984, Example 1 | (R)-5-Biphenyl-4-yl-2-hydr...)
Affinity DataKi:  35.5nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298318BDBM298318(US10123984, Example 11-3 | US10744104, Example 11-...)
Affinity DataKi:  35.5nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298320BDBM298320(US10123984, Example 12 | 3-(N-Biphenyl-4-ylmethyl-...)
Affinity DataKi:  35.5nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 50034854BDBM50034854((2R,4S)-5-Biphenyl-4-yl-4-(4-carboxy-butyrylamino)...)
Affinity DataIC50: 90nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 298276BDBM298276(US10123984, Compound 21g)
Affinity DataIC50: 92nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 50034868BDBM50034868((2S,4R)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...)
Affinity DataIC50: 190nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 50034857BDBM50034857((2R,4S)-5-Biphenyl-4-yl-4-(5-carboxy-pentanoylamin...)
Affinity DataIC50: 324nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 50034865BDBM50034865((2S,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...)
Affinity DataIC50: 700nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent