Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 927
TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299173BDBM299173(US10125144, Example 1 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 2nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299190BDBM299190(US10125144, Example 18 | N-(4-(1H-pyrazol-4-yl)phe...)
Affinity DataIC50: 2nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299179BDBM299179(US10125144, Example 7 | N-(1H-Indazol-5-yl)-2-(5-m...)
Affinity DataIC50: 10nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299173BDBM299173(US10125144, Example 1 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 10nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299188BDBM299188(US10125144, Example 16 | N-(2-(5-Methoxyisoindolin...)
Affinity DataIC50: 10nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299175BDBM299175(US10125144, Example 3 | N-(5-Fluoro-2-(5-methoxyis...)
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299178BDBM299178(US10125144, Example 6 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299192BDBM299192(US10125144, Example 20 | 2-(5-Methoxyisoindolin-2-...)
Affinity DataIC50: 35nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299192BDBM299192(US10125144, Example 20 | 2-(5-Methoxyisoindolin-2-...)
Affinity DataIC50: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299181BDBM299181(US10125144, Example 9 | N-(2-(5-Fluoroisoindolin-2...)
Affinity DataIC50: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299177BDBM299177(US10125144, Example 5 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 50nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299174BDBM299174(US10125144, Example 2 | N-(2-(Isoindolin-2-yl)pyri...)
Affinity DataIC50: 60nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299198BDBM299198(US10125144, Example 27 | N-(2-(5-(Methoxymethyl)is...)
Affinity DataIC50: 100nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299199BDBM299199(US10125144, Example 28 | N-(2-(4-Methoxyisoindolin...)
Affinity DataIC50: 100nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299182BDBM299182(US10125144, Example 10 | N-(2-(5-Chloroisoindolin-...)
Affinity DataIC50: 110nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299197BDBM299197(US10125144, Example 26 | 2-(4-((1H-Indazol-5-yl)am...)
Affinity DataIC50: 123nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299185BDBM299185(US10125144, Example 13 | N-(6-(5-Methoxyisoindolin...)
Affinity DataIC50: 130nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299196BDBM299196(US10125144, Example 25 | N-(1H-Indazol-5-yl)-2-(5-...)
Affinity DataIC50: 130nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299176BDBM299176(US10125144, Example 4 | N-(5-Chloro-2-(5-methoxyis...)
Affinity DataIC50: 140nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299186BDBM299186(US10125144, Example 14 | N-(6-(5-Methoxyisoindolin...)
Affinity DataIC50: 155nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299193BDBM299193(US10125144, Example 21 | N-(1H-Indazol-5-yl)-2-(5-...)
Affinity DataIC50: 185nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299176BDBM299176(US10125144, Example 4 | N-(5-Chloro-2-(5-methoxyis...)
Affinity DataIC50: 190nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299187BDBM299187(US10125144, Example 15 | N-(2-(1H-Pyrrolo[3,4-c]py...)
Affinity DataIC50: 340nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299173BDBM299173(US10125144, Example 1 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 434nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299202BDBM299202(US10125144, Example 32 | N-(2-(Isoindolin-2-yl)-5,...)
Affinity DataIC50: 607nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299183BDBM299183(US10125144, Example 11 | N-(2-(6-Methoxy-3,4-dihyd...)
Affinity DataIC50: 700nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299200BDBM299200(US10125144, Example 29 | N-(2-(4-Fluoroisoindolin-...)
Affinity DataIC50: 880nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299173BDBM299173(US10125144, Example 1 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 893nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299184BDBM299184(US10125144, Example 12 | N-(2-(6,7-Dihydrothieno[3...)
Affinity DataIC50: 1.06E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299180BDBM299180(US10125144, Example 8 | N-(4-(5-Methoxyisoindolin-...)
Affinity DataIC50: 1.17E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299178BDBM299178(US10125144, Example 6 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 2.37E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299195BDBM299195(US10125144, Example 24 | N-(1H-Indazol-5-yl)-2-(5-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299181BDBM299181(US10125144, Example 9 | N-(2-(5-Fluoroisoindolin-2...)
Affinity DataIC50: 2.93E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299194BDBM299194(US10125144, Example 22 | (KL-00254) N-(1H-Indazol-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299179BDBM299179(US10125144, Example 7 | N-(1H-Indazol-5-yl)-2-(5-m...)
Affinity DataIC50: 3.75E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299198BDBM299198(US10125144, Example 27 | N-(2-(5-(Methoxymethyl)is...)
Affinity DataIC50: 6.73E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299175BDBM299175(US10125144, Example 3 | N-(5-Fluoro-2-(5-methoxyis...)
Affinity DataIC50: 8.34E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299177BDBM299177(US10125144, Example 5 | N-(2-(5-Methoxyisoindolin-...)
Affinity DataIC50: 8.57E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299182BDBM299182(US10125144, Example 10 | N-(2-(5-Chloroisoindolin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299183BDBM299183(US10125144, Example 11 | N-(2-(6-Methoxy-3,4-dihyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299201BDBM299201(US10125144, Example 30 | 2-(5-Fluoroisoindolin-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299184BDBM299184(US10125144, Example 12 | N-(2-(6,7-Dihydrothieno[3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299202BDBM299202(US10125144, Example 32 | N-(2-(Isoindolin-2-yl)-5,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299185BDBM299185(US10125144, Example 13 | N-(6-(5-Methoxyisoindolin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299194BDBM299194(US10125144, Example 22 | (KL-00254) N-(1H-Indazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299180BDBM299180(US10125144, Example 8 | N-(4-(5-Methoxyisoindolin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299196BDBM299196(US10125144, Example 25 | N-(1H-Indazol-5-yl)-2-(5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299197BDBM299197(US10125144, Example 26 | 2-(4-((1H-Indazol-5-yl)am...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299174BDBM299174(US10125144, Example 2 | N-(2-(Isoindolin-2-yl)pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Kadmon

US Patent
LigandChemical structure of BindingDB Monomer ID 299191BDBM299191(US10125144, Example 19 | 2-(5-Methoxyisoindolin-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

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