Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with all data for entry = 1024
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303361BDBM303361(US10138222, Example 76)
Affinity DataIC50: 0.610nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303364BDBM303364(BDBM303369 | US10138222, Example 79)
Affinity DataIC50: 0.810nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303360BDBM303360(US10138222, Example 75)
Affinity DataIC50: 0.900nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303438BDBM303438(US10138222, Example 166)
Affinity DataIC50: 0.940nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303440BDBM303440(US10138222, Example 168)
Affinity DataIC50: 0.950nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303380BDBM303380(US10138222, Example 105)
Affinity DataIC50: 1nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303439BDBM303439(US10138222, Example 167)
Affinity DataIC50: 1nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303359BDBM303359(US10138222, Example 74)
Affinity DataIC50: 1nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303362BDBM303362(US10138222, Example 77)
Affinity DataIC50: 1.10nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303432BDBM303432(US10138222, Example 160)
Affinity DataIC50: 1.10nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303435BDBM303435(US10138222, Example 163)
Affinity DataIC50: 1.10nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303355BDBM303355(US10138222, Example 68)
Affinity DataIC50: 1.10nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303437BDBM303437(US10138222, Example 165)
Affinity DataIC50: 1.20nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303430BDBM303430(US10138222, Example 158)
Affinity DataIC50: 1.20nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303363BDBM303363(US10138222, Example 78)
Affinity DataIC50: 1.30nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303441BDBM303441(US10138222, Example 169)
Affinity DataIC50: 1.30nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303364BDBM303364(BDBM303369 | US10138222, Example 79)
Affinity DataIC50: 1.40nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303443BDBM303443(US10138222, Example 171)
Affinity DataIC50: 1.40nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303448BDBM303448(US10138222, Example 176)
Affinity DataIC50: 1.5nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303433BDBM303433(US10138222, Example 161)
Affinity DataIC50: 1.5nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303367BDBM303367(US10138222, Example 92)
Affinity DataIC50: 1.5nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303368BDBM303368(US10138222, Example 93)
Affinity DataIC50: 1.5nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303446BDBM303446(US10138222, Example 174)
Affinity DataIC50: 1.5nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303353BDBM303353(US10138222, Example 67)
Affinity DataIC50: 1.60nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303425BDBM303425(US10138222, Example 153)
Affinity DataIC50: 1.60nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303428BDBM303428(US10138222, Example 156)
Affinity DataIC50: 1.60nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303447BDBM303447(US10138222, Example 175)
Affinity DataIC50: 1.70nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303427BDBM303427(US10138222, Example 155)
Affinity DataIC50: 1.70nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303431BDBM303431(US10138222, Example 159)
Affinity DataIC50: 1.80nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303426BDBM303426(US10138222, Example 154)
Affinity DataIC50: 1.80nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303442BDBM303442(US10138222, Example 170)
Affinity DataIC50: 1.80nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303444BDBM303444(US10138222, Example 172)
Affinity DataIC50: 1.80nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303445BDBM303445(US10138222, Example 173)
Affinity DataIC50: 1.80nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303345BDBM303345(US10138222, Example 63)
Affinity DataIC50: 1.90nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303429BDBM303429(US10138222, Example 157)
Affinity DataIC50: 1.90nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303379BDBM303379(US10138222, Example 104)
Affinity DataIC50: 1.90nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303436BDBM303436(US10138222, Example 164)
Affinity DataIC50: 2.10nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303434BDBM303434(US10138222, Example 162)
Affinity DataIC50: 2.30nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303351BDBM303351(US10138222, Example 65)
Affinity DataIC50: 2.30nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303376BDBM303376(US10138222, Example 99)
Affinity DataIC50: 2.60nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303412BDBM303412(US10138222, Example 141)
Affinity DataIC50: 2.60nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303390BDBM303390(US10138222, Example 114)
Affinity DataIC50: 2.70nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303356BDBM303356(US10138222, Example 71)
Affinity DataIC50: 2.70nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303391BDBM303391(US10138222, Example 115)
Affinity DataIC50: 2.70nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303415BDBM303415(US10138222, Example 144)
Affinity DataIC50: 2.90nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303413BDBM303413(US10138222, Example 142)
Affinity DataIC50: 3.20nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303382BDBM303382(US10138222, Example 107)
Affinity DataIC50: 3.30nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303372BDBM303372(US10138222, Example 97)
Affinity DataIC50: 3.30nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303385BDBM303385(US10138222, Example 110)
Affinity DataIC50: 3.40nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 303393BDBM303393(US10138222, Example 117)
Affinity DataIC50: 3.40nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

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