Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 1050
TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 21675BDBM21675(6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...)
Affinity DataEC50:  550nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304498BDBM304498(US10144729, Example 2b)
Affinity DataEC50:  550nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304715BDBM304715(US10144729, Example 2c)
Affinity DataEC50:  550nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304716BDBM304716(US10144729, Example 2d)
Affinity DataEC50:  550nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304717BDBM304717(US10144729, Example 1a)
Affinity DataEC50:  550nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304497BDBM304497(US10144729, Example 2a)
Affinity DataEC50:  5.50E+3nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304718BDBM304718(US10144729, Example 1b)
Affinity DataEC50:  5.50E+3nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 21674BDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50: >1.00E+4nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)