Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 1114
TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310190(US10150758, Compound 6)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310191(US10150758, Compound 7 | 4-(4-chlorophenyl)-1-(3-(...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310192(US10150758, Compound 8 | 1-(3-(3,4-dihydroisoquino...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310196(US10150758, Compound 12 | 1-(3-(3,4-dihydroisoquin...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310188(US10150758, Compound 4 | 1-(3-(3,4-dihydroisoquino...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310189(US10150758, Compound 5 | 4-(3-chlorophenyl)-1-(3-(...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310202(US10150758, Compound 18 | BDBM310203)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310215(US10150758, Compound 31 | 4-(3-(3,4-dihydroisoquin...)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310204(US10150758, Compound 20)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310217(US10150758, Compound 33)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310193(US10150758, Compound 9)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310185(US10150758, Compound 1 | 1-(3-(3,4-dihydroisoquino...)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310213(US10150758, Compound 29)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310199(US10150758, Compound 15 | 1-(3-(3,4-dihydroisoquin...)
Affinity DataIC50: 550nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310201(US10150758, Compound 17)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310214(US10150758, Compound 30)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310200(US10150758, Compound 16)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310202(US10150758, Compound 18 | BDBM310203)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310205(US10150758, Compound 21)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310218(US10150758, Compound 34)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310207(US10150758, Compound 23)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310206(US10150758, Compound 22)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310209(US10150758, Compound 25)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310208(US10150758, Compound 24)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310210(US10150758, Compound 26)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310212(US10150758, Compound 28)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310216(US10150758, Compound 32)
Affinity DataIC50: 1.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310187(US10150758, Compound 3 | 1-(3-(3,4-dihydroisoquino...)
Affinity DataIC50: 3.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310186(US10150758, Compound 2)
Affinity DataIC50: 3.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM310211(US10150758, Compound 27)
Affinity DataIC50: 5.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent