Compile Data Set for Download or QSAR
Report error Found 241 Enz. Inhib. hit(s) with all data for entry = 1232
TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164901BDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 0.100nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164943BDBM164943(US9067914, Ex. 3-40-3 | US10166239, Ex. 3-40-3 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164944BDBM164944(US9067914, Ex. 3-40-4 | US10166239, Ex. 3-40-4 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164902BDBM164902(US9067914, Ex. 3-16 | US10166239, Ex. 3-16 | US114...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164945BDBM164945(US9067914, Ex. 3-40-5 | US10166239, Ex. 3-40-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164945BDBM164945(US9067914, Ex. 3-40-5 | US10166239, Ex. 3-40-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164930BDBM164930(US9067914, Ex. 3-35-4 | US10166239, Ex. 3-35-4 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164941BDBM164941(US9067914, Ex. 3-40-1 | US10166239, Ex. 3-40-1 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164930BDBM164930(US9067914, Ex. 3-35-4 | US10166239, Ex. 3-35-4 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164941BDBM164941(US9067914, Ex. 3-40-1 | US10166239, Ex. 3-40-1 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164931BDBM164931(US9067914, Ex. 3-35-5 | US10166239, Ex. 3-35-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164942BDBM164942(US9067914, Ex. 3-40-2 | US10166239, Ex. 3-40-2 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164943BDBM164943(US9067914, Ex. 3-40-3 | US10166239, Ex. 3-40-3 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164928BDBM164928(US9067914, Ex. 3-35-2 | US10166239, Ex. 3-35-2 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164928BDBM164928(US9067914, Ex. 3-35-2 | US10166239, Ex. 3-35-2 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164929BDBM164929(US9067914, Ex. 3-35-3 | US10166239, Ex. 3-35-3 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164901BDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 0.300nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164927BDBM164927(US9067914, Ex. 3-35-1 | US10166239, Ex. 3-35-1 | U...)
Affinity DataIC50: 0.300nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164944BDBM164944(US9067914, Ex. 3-40-4 | US10166239, Ex. 3-40-4 | U...)
Affinity DataIC50: 0.300nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164956BDBM164956(US9067914, Ex. 3-49-6a | US10166239, Ex. 3-49-6a |...)
Affinity DataIC50: 0.300nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164929BDBM164929(US9067914, Ex. 3-35-3 | US10166239, Ex. 3-35-3 | U...)
Affinity DataIC50: 0.300nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164940BDBM164940(US9067914, Ex. 3-39 | US10166239, Ex. 3-39 | US114...)
Affinity DataIC50: 0.300nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164962BDBM164962(US9067914, Ex. 3-53 | US10166239, Ex. 3-53 | US114...)
Affinity DataIC50: 0.400nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164931BDBM164931(US9067914, Ex. 3-35-5 | US10166239, Ex. 3-35-5 | U...)
Affinity DataIC50: 0.5nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164885BDBM164885(US9067914, Ex. 3-1 | US10166239, Ex. 3-1 | US11406...)
Affinity DataIC50: 0.5nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164902BDBM164902(US9067914, Ex. 3-16 | US10166239, Ex. 3-16 | US114...)
Affinity DataIC50: 0.5nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164901BDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 0.503nMAssay Description:Human TrkC, catalytic domain [456-825(end) amino acids of accession number NP_002521.2] was expressed as N-terminal GST-fusion protein (69 kDa) using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164942BDBM164942(US9067914, Ex. 3-40-2 | US10166239, Ex. 3-40-2 | U...)
Affinity DataIC50: 0.600nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164962BDBM164962(US9067914, Ex. 3-53 | US10166239, Ex. 3-53 | US114...)
Affinity DataIC50: 0.600nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164927BDBM164927(US9067914, Ex. 3-35-1 | US10166239, Ex. 3-35-1 | U...)
Affinity DataIC50: 0.600nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164912BDBM164912(US9067914, Ex. 3-20 | US10166239, Ex. 3-20 | US114...)
Affinity DataIC50: 0.600nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164956BDBM164956(US9067914, Ex. 3-49-6a | US10166239, Ex. 3-49-6a |...)
Affinity DataIC50: 0.600nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164940BDBM164940(US9067914, Ex. 3-39 | US10166239, Ex. 3-39 | US114...)
Affinity DataIC50: 0.600nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164937BDBM164937(US9067914, Ex. 3-37-5 | US10166239, Ex. 3-37-5 | U...)
Affinity DataIC50: 0.700nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164911BDBM164911(US9067914, Ex. 3-19 | US10166239, Ex. 3-19 | US114...)
Affinity DataIC50: 0.900nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164912BDBM164912(US9067914, Ex. 3-20 | US10166239, Ex. 3-20 | US114...)
Affinity DataIC50: 0.900nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164888BDBM164888(US9067914, Ex. 3-2-3 | US10166239, Ex. 3-2-3 | US1...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164961BDBM164961(US9067914, Ex. 3-52 | US10166239, Ex. 3-52 | US114...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164911BDBM164911(US9067914, Ex. 3-19 | US10166239, Ex. 3-19 | US114...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164964BDBM164964(US9067914, Ex. 3-55 | US10166239, Ex. 3-55 | US114...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 164889BDBM164889(US9067914, Ex. 3-3 | US10166239, Ex. 3-3 | US11406...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, c-FMS (0.14 nM, Carna 08-155) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164885BDBM164885(US9067914, Ex. 3-1 | US10166239, Ex. 3-1 | US11406...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164964BDBM164964(US9067914, Ex. 3-55 | US10166239, Ex. 3-55 | US114...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164950BDBM164950(US9067914, Ex. 3-45 | US10166239, Ex. 3-45 | US114...)
Affinity DataIC50: 1nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 164887BDBM164887(US9067914, Ex. 3-2-2 | US10166239, Ex. 3-2-2 | US1...)
Affinity DataIC50: 2nMAssay Description:In a 384 well polypropylene plate, c-FMS (0.14 nM, Carna 08-155) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164937BDBM164937(US9067914, Ex. 3-37-5 | US10166239, Ex. 3-37-5 | U...)
Affinity DataIC50: 2nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 164937BDBM164937(US9067914, Ex. 3-37-5 | US10166239, Ex. 3-37-5 | U...)
Affinity DataIC50: 2nMAssay Description:In a 384 well polypropylene plate, c-FMS (0.14 nM, Carna 08-155) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 164911BDBM164911(US9067914, Ex. 3-19 | US10166239, Ex. 3-19 | US114...)
Affinity DataIC50: 2nMAssay Description:In a 384 well polypropylene plate, c-FMS (0.14 nM, Carna 08-155) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandChemical structure of BindingDB Monomer ID 164938BDBM164938(US9067914, Ex. 3-37-6 | US10166239, Ex. 3-37-6 | U...)
Affinity DataIC50: 2nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 164901BDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 2nMAssay Description:In a 384 well polypropylene plate, c-FMS (0.14 nM, Carna 08-155) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

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