Compile Data Set for Download or QSAR
Report error Found 103 Enz. Inhib. hit(s) with all data for entry = 1370
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318917BDBM318917(US10172868, Compound C156 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318917BDBM318917(US10172868, Compound C156 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318916BDBM318916(US10172868, Compound C151 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318916BDBM318916(US10172868, Compound C151 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318916BDBM318916(US10172868, Compound C151 | N-(3-(2-((2,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318869BDBM318869(US10172868, Compound C032 | N-(3-(2-((4-(4-acetylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318870BDBM318870(US10172868, Compound C034 | N-(3-(7-methyl-2-((4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318870BDBM318870(US10172868, Compound C034 | N-(3-(7-methyl-2-((4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318866BDBM318866(US10172868, Compound C001 | N-(3-(2-((4-morpholino...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318867BDBM318867(US10172868, Compound C003 | N-(3-(2-((2-methoxy-4-...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318868BDBM318868(US10172868, Compound C021 | N-(3-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318873BDBM318873(US10172868, Compound C044 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318873BDBM318873(US10172868, Compound C044 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318873BDBM318873(US10172868, Compound C044 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318873BDBM318873(US10172868, Compound C044 | N-(3-(2-((2-fluoro-4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318875BDBM318875(US10172868, Compound C048 | N-(2-fluoro-3-(2-((6-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318874BDBM318874(US10172868, Compound C045 | N-(2-fluoro-3-(2-((4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318871BDBM318871(US10172868, Compound C040 | N-(5-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318871BDBM318871(US10172868, Compound C040 | N-(5-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318872BDBM318872(US10172868, Compound C041 | N-(3-(2-((6-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318872BDBM318872(US10172868, Compound C041 | N-(3-(2-((6-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318872BDBM318872(US10172868, Compound C041 | N-(3-(2-((6-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318872BDBM318872(US10172868, Compound C041 | N-(3-(2-((6-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318872BDBM318872(US10172868, Compound C041 | N-(3-(2-((6-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318872BDBM318872(US10172868, Compound C041 | N-(3-(2-((6-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318880BDBM318880(US10172868, Compound C061 | N-(2-fluoro-3-(2-((4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318882BDBM318882(US10172868, Compound C067 | N-(4-fluoro-3-(2-((4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318881BDBM318881(US10172868, Compound C063 | N-(2-methoxy-3-(2-((4-...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318884BDBM318884(US10172868, Compound C072 | N-(3-(2-((3-chloro-4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318883BDBM318883(US10172868, Compound C068 | N-(2-cyano-3-(2-((4-(4...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318876BDBM318876(US10172868, Compound C049 | N-(3-(2-((4-(4-acetylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318875BDBM318875(US10172868, Compound C048 | N-(2-fluoro-3-(2-((6-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318878BDBM318878(US10172868, Compound C057 | N-(4-(2-((4-(4-methylp...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318877BDBM318877(US10172868, Compound C054 | N-(2-chloro-3-(2-((4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318879BDBM318879(US10172868, Compound C059 | N-(3-(2-((4-(4-(2-hydr...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318891BDBM318891(US10172868, Compound C081 | N-(3-(2-((5-chloro-6-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318892BDBM318892(US10172868, Compound C085 | 5-((8-(3-acrylamidophe...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318892BDBM318892(US10172868, Compound C085 | 5-((8-(3-acrylamidophe...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 318894BDBM318894(US10172868, Compound C088 | N-(3-(7-fluoro-2-((4-(...)
Affinity DataIC50: 100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

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