Compile Data Set for Download or QSAR
Report error Found 117 Enz. Inhib. hit(s) with all data for entry = 1468
TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324744BDBM324744(1'-({5-Chloro-1-[2-(1,1- dioxidothietan-3-yl)ethyl...)
Affinity DataEC50:  1.10nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324745BDBM324745(1'-({5-Chloro-1-[3- (methylsulfonyl)propyl]-1H- be...)
Affinity DataEC50:  2nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324714BDBM324714(1'-({5-Chloro-1-[3- (ethylsulfonyl)propyl]-1H-indo...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324749BDBM324749(1'-{[5-Chloro-1-(oxetan-3-ylmethyl)- 1H-benzimidaz...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324694BDBM324694(US10189838, Example 10 | 1''-[{5-Chloro-1-[3- (met...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324750BDBM324750(1'-({5-Chloro-1-[2-(oxetan-3- yl)ethyl]-1H-benzimi...)
Affinity DataEC50:  3nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324648BDBM324648(1'-({5-Chloro-7-fluoro-1-[2- (methylsulfonyl)ethyl...)
Affinity DataEC50:  3.40nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324737BDBM324737(1'-({6-Chloro-3-[2- (methylsulfonyl)ethyl]-1H-indo...)
Affinity DataEC50:  5nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324663BDBM324663(1'-({5-Chloro-1-[4- (methylsulfonyl)butyl]-1H-indo...)
Affinity DataEC50:  5.90nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324729BDBM324729(1'-[(5-Chloro-1-{2-[4- (methylsulfonyl)piperazin-1...)
Affinity DataEC50:  6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324698BDBM324698(1'-({5-Chloro-1-[3-(S- methylsulfomidoyl)propyl]-1...)
Affinity DataEC50:  6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324738BDBM324738(1'-({6-Chloro-3-[3- (methylsulfonyl)propyl]-1H-ind...)
Affinity DataEC50:  6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324699BDBM324699(1'-({5-Chloro-1-[2-(S- methylsulfonimidoyl)ethyl]-...)
Affinity DataEC50:  7nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324682BDBM324682(3-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  7nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324687BDBM324687(1'-[(5-Chloro-1-{3-[(3-oxopiperazin- 1-yl)sulfonyl...)
Affinity DataEC50:  7nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324651BDBM324651(1'-({5-Chloro-1-[2- (ethylsulfonyl)ethyl]-1H-indol...)
Affinity DataEC50:  7.67nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324746BDBM324746(1'-({5-Chloro-1-[2- (cyclopropylsulfonyl)ethyl]-1H...)
Affinity DataEC50:  8nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324649BDBM324649(1'-({5-Methyl-1-[2- (methylsulfonyl)ethyl]-1H-indo...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324747BDBM324747(1'-({5-Chloro-7-fluoro-1-[2- (methylsulfonyl)ethyl...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324736BDBM324736(1'-({6-Chloro-3-[2- (ethylsulfonyl)ethyl]-1H-indol...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324679BDBM324679(1'-({5-Chloro-1-[3- (methylsulfinyl)propyl]-1H-ind...)
Affinity DataEC50:  9nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324708BDBM324708(4-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  11nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324724BDBM324724(3-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  11nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324730BDBM324730(N-(2-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'-...)
Affinity DataEC50:  11.5nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324739BDBM324739(1'-({5-Chloro-1-[2- (methylsulfonyl)ethyl]-1H- ben...)
Affinity DataEC50:  12nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324743BDBM324743(1'-({5-Chloro-1-[2- (ethylsulfonyl)ethyl]-1H- benz...)
Affinity DataEC50:  13nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324685BDBM324685(1'-({5-Chloro-1-[3-(morpholin-4- ylsulfonyl)propyl...)
Affinity DataEC50:  14nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324641BDBM324641(1'-({5-Bromo-1-[2- (methylsulfonyl)ethyl]-1H-indol...)
Affinity DataEC50:  14nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324719BDBM324719(1'-({5-Chloro-1-[3-(piperazin-1- ylsulfonyl)propyl...)
Affinity DataEC50:  15nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324748BDBM324748(1'-({5,7-Dichloro-1-[2- (methylsulfonyl)ethyl]-1H-...)
Affinity DataEC50:  16.8nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324706BDBM324706(3-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  17nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324697BDBM324697(Ethyl 3-{5-chloro-7-fluoro-2-[(2'- oxospiro[cyclop...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324673BDBM324673(1'-({5-Chloro-1-[2-(1,1- dioxidothietan-3-yl)ethyl...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324689BDBM324689(1'-({5-Chloro-1-[4-(1,1-dioxido-1,2- thiazolidin-2...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324752BDBM324752(1'-({1-[(3-Aminooxetan-3- yl)methyl]-5-chloro-1H- ...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324677BDBM324677(1'-({5-Chloro-1-[3- (methylsulfonyl)propyl]-1H- py...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324662BDBM324662(US10189838, Example 3-3 | 1''-({5-Chloro-1-[2- (me...)
Affinity DataEC50:  18nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324705BDBM324705(Methyl 4-{5-chloro-2-[(2'- oxospiro[cyclopropane-1...)
Affinity DataEC50:  18.6nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324652BDBM324652(1'-({5-Chloro-1-[2- (ethylsulfonyl)ethyl]-1H-pyrro...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324720BDBM324720(1'-[(5-Chloro-1-{3-[(1R,4R)-2,5- diazabicyclo[2.2....)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324662BDBM324662(US10189838, Example 3-3 | 1''-({5-Chloro-1-[2- (me...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324695BDBM324695(Ethyl 3-{5-chloro-2-[(2'- oxospiro[cyclopropane-1,...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324694BDBM324694(US10189838, Example 10 | 1''-[{5-Chloro-1-[3- (met...)
Affinity DataEC50:  19nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324686BDBM324686(1'-({5-Chloro-1-[3-(pyrrolidin-1- ylsulfonyl)propy...)
Affinity DataEC50:  20nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324734BDBM324734(Methyl (3-{5-chloro-2-[(2'- oxospiro[cyclopropane-...)
Affinity DataEC50:  20nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324740BDBM324740(1'-({5-Chloro-1-[2- (methylsulfonyl)ethyl]-1H- ben...)
Affinity DataEC50:  20nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324667BDBM324667(1'-({5-Chloro-1-[4- (methylsulfonyl)butyl]-1H- pyr...)
Affinity DataEC50:  22.1nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324684BDBM324684(2-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'- py...)
Affinity DataEC50:  23nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324645BDBM324645(1'-({5,7-Difluoro-1-[2- (methylsulfonyl)ethyl]-1H-...)
Affinity DataEC50:  24nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

TargetProtein M2-1(Human respiratory syncytial virus A (strain A2))
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 324728BDBM324728(N-(2-{5-Chloro-2-[(2'- oxospiro[cyclopropane-1,3'-...)
Affinity DataEC50:  25nMAssay Description:To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details
US Patent

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