Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 1594
TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332051BDBM332051(US10196346, Example 33 | (E)-N'-(4-N,N-diethylamin...)
Affinity DataEC50:  130nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332034BDBM332034(US10196346, Example 11 | (E)-N'-(2,3- dihydroxyben...)
Affinity DataEC50:  170nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332048BDBM332048(US10196346, Example 30 | (E)-N'-(4-N,N-diethylamin...)
Affinity DataEC50:  530nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332038BDBM332038(US10196346, Example 17 | (E)-N'-(2,3- dihydroxyben...)
Affinity DataEC50:  560nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332033BDBM332033(US10196346, Example 10 | (E)-N'-(4-N,N- diethylami...)
Affinity DataEC50:  600nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332041BDBM332041(US10196346, Example 23 | (E)-N'-(4-N,N- diethylami...)
Affinity DataEC50:  760nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332031BDBM332031(US10196346, Example 5 | (E)-N'-(4-N,N- diethylamin...)
Affinity DataEC50:  780nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332035BDBM332035(US10196346, Example 13 | (E)-N'-[(3-ethoxy-2- hydr...)
Affinity DataEC50:  800nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332042BDBM332042(US10196346, Example 24 | (E)-N'-(2,3- dihydroxyben...)
Affinity DataEC50:  820nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332030BDBM332030(US10196346, Example 4 | (E)-N'-[(2- hydroxynaphtha...)
Affinity DataEC50:  830nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332044BDBM332044(US10196346, Example 26 | (E)-N'-[(2- hydroxynaphth...)
Affinity DataEC50:  980nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332036BDBM332036(US10196346, Example 14 | (E)-N'-[(2- hydroxynaphth...)
Affinity DataEC50:  1.02E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332050BDBM332050(US10196346, Example 32 | (E)-N'-(3-ethoxy-2- hydro...)
Affinity DataEC50:  1.86E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332029BDBM332029(US10196346, Example 3 | (E)-N'-(3-ethoxy-2- hydrox...)
Affinity DataEC50:  2.11E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332039BDBM332039(US10196346, Example 18 | (E)-N'-(3-bromo-6- hydrox...)
Affinity DataEC50:  2.28E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332027BDBM332027(US10196346, Example 1 | (E)-N'-(3-methoxy-2- hydro...)
Affinity DataEC50:  2.29E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332049BDBM332049(US10196346, Example 31 | (E)-N'-(3-methoxy-2- hydr...)
Affinity DataEC50:  2.76E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332047BDBM332047(US10196346, Example 29 | (E)-N'-(3-ethoxy-2- hydro...)
Affinity DataEC50:  2.77E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332040BDBM332040(US10196346, Example 22 | (E)-N'-(3,5-di-tert-butyl...)
Affinity DataEC50:  2.77E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332032BDBM332032(US10196346, Example 8 | (E)-N'-(3,5-di-tert-butyl-...)
Affinity DataEC50:  5.23E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332043BDBM332043(US10196346, Example 25 | (E)-N'-(3-bromo-6- hydrox...)
Affinity DataEC50:  7.19E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332045BDBM332045(US10196346, Example 27 | (E)-N'-(3,5-di-tert-butyl...)
Affinity DataEC50:  7.75E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332046BDBM332046(US10196346, Example 28 | (E)-N'-(3-methoxy-2- hydr...)
Affinity DataEC50:  8.42E+3nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332037BDBM332037(US10196346, Example 15 | (E)-N'-(3,5-di-tert-butyl...)
Affinity DataEC50:  1.12E+4nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 332028BDBM332028(US10196346, Example 2 | (E)-N'-(3,5-di-tert-butyl-...)
Affinity DataEC50:  1.78E+4nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China

US Patent
LigandChemical structure of BindingDB Monomer ID 50042874BDBM50042874(2,2'-bipyridine | 2,2'-Bipyridin | 2,2'-bipyridyl ...)
Affinity DataEC50:  4.14E+4nMAssay Description:The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent