Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 1610
TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332747(US10196381, Compound (37) | 2-(4-(5-cyanopyrazin-2...)
Affinity DataIC50: 3nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332743(US10196381, Compound (33))
Affinity DataIC50: 5nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332748(US10196381, Compound (38) | 2-(4-(2-cyanopyrimidin...)
Affinity DataIC50: 6nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332736(US10196381, Compound (26) | 2-(4-(5-ethylcarbamoyl...)
Affinity DataIC50: 7nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332735(US10196381, Compound (25) | 6-fluoro-2-(4-(5-methy...)
Affinity DataIC50: 7nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332741(US10196381, Compound (31) | 6-fluoro-2-(4-(6-trifl...)
Affinity DataIC50: 8nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332746(US10196381, Compound (36) | 2-(4-(5-dimethylcarbam...)
Affinity DataIC50: 8nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332751(US10196381, Compound (41) | 2-(4-(2-dimethylcarbam...)
Affinity DataIC50: 8nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332740(US10196381, Compound (30) | 6-fluoro-2-(4-(5-(morp...)
Affinity DataIC50: 9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332725(US10196381, Compound (16))
Affinity DataIC50: 9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332728(US10196381, Compound (19) | 2-(4-(5-cyanopyrimidin...)
Affinity DataIC50: 9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332745(US10196381, Compound (35) | 6-fluoro-2-(4-(5-trifl...)
Affinity DataIC50: 9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332749(US10196381, Compound (39) | 6-fluoro-2-(4-(2-methy...)
Affinity DataIC50: 9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332750(US10196381, Compound (40) | 2-(4-(2-ethylcarbamoyl...)
Affinity DataIC50: 9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332731(US10196381, Compound (22) | 6-fluoro-2-(4-(5-methy...)
Affinity DataIC50: 10nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332739(US10196381, Compound (29) | 6-fluoro-2-(4-(5-(pyrr...)
Affinity DataIC50: 12nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332732(US10196381, Compound (23) | 6-fluoro-2-(4-(6-methy...)
Affinity DataIC50: 12nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332737(US10196381, Compound (27) | 6-fluoro-2-(4-(5-isopr...)
Affinity DataIC50: 14nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332742(US10196381, Compound (32) | 6-fluoro-2-(4-(6-trifl...)
Affinity DataIC50: 15nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332714(US10196381, Compound (7) | 2-(4-(pyrimidin-4-yl)pi...)
Affinity DataIC50: 17nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332718(US10196381, Compound (11) | 2-(4-(5-methylcarbamoy...)
Affinity DataIC50: 25nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332721(US10196381, Compound (12) | 2-(4-(5-carbamoylpyrid...)
Affinity DataIC50: 25nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332738(US10196381, Compound (28) | 2-(4-(5-t-butylcarbamo...)
Affinity DataIC50: 25nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332726(US10196381, Compound (17) | 6-fluoro-2-(4-(5-fluor...)
Affinity DataIC50: 26nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332723(US10196381, Compound (14) | 2-(4-(5-cyanopyrimidin...)
Affinity DataIC50: 28nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332727(US10196381, Compound (18) | 2-(4-(5-(dimethylcarba...)
Affinity DataIC50: 30nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332734(US10196381, Compound (24) | 6-fluoro-2-(4-(5-methy...)
Affinity DataIC50: 45nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332708(US10196381, Compound (1))
Affinity DataIC50: 48nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332729(US10196381, Compound (20) | 6-fluoro-2-(4-(3-methy...)
Affinity DataIC50: 48nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332722(US10196381, Compound (13) | 2-(4-(2-trifluoromethy...)
Affinity DataIC50: 49nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332709(US10196381, Compound (2))
Affinity DataIC50: 49nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332724(US10196381, Compound (15) | 2-(4-(5-dimethylcarbam...)
Affinity DataIC50: 54nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332717(US10196381, Compound (10) | 2-(4-(6-trifluoromethy...)
Affinity DataIC50: 55nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332744(US10196381, Compound (34) | 6-fluoro-2-(4-(5-trifl...)
Affinity DataIC50: 56nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332730(US10196381, Compound (21) | 6-fluoro-2-(4-(5-trifl...)
Affinity DataIC50: 68nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332712(US10196381, Compound (5) | 2-(4-(5-methoxypyrimidi...)
Affinity DataIC50: 74nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332713(US10196381, Compound (6) | 2-(4-(5-aminopyrimidin-...)
Affinity DataIC50: 98nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332711(US10196381, Compound (4) | 2-(4-(5-acetamidopyrimi...)
Affinity DataIC50: 106nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332716(US10196381, Compound (9) | 2-(4-(4-trifluoromethyl...)
Affinity DataIC50: 217nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332715(US10196381, Compound (8) | 2-(4-(3-ethylaminopyrid...)
Affinity DataIC50: 928nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332710(US10196381, Compound (3) | 2-(4-(5-ethylaminopyrim...)
Affinity DataIC50: 3.58E+3nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent