Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 1614
TargetProbable G-protein coupled receptor 142(Human)
Eli Lilly

US Patent
LigandPNGBDBM332764(US10196385, Example 3 | Cis-(chiral)-3-Chloro-N-[2...)
Affinity DataEC50:  27.2nMAssay Description:HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37° C. and 5% CO2. The c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetProbable G-protein coupled receptor 142(Human)
Eli Lilly

US Patent
LigandPNGBDBM332763(US10196385, Example 2 | Cis-(chiral)-N-[2-[5-(1,4-...)
Affinity DataEC50:  30.1nMAssay Description:HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37° C. and 5% CO2. The c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetProbable G-protein coupled receptor 142(Human)
Eli Lilly

US Patent
LigandPNGBDBM332762(US10196385, Example 1 | Cis-(chiral)-N-[(2-[5-(1,4...)
Affinity DataEC50:  43.5nMAssay Description:HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37° C. and 5% CO2. The c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent