Compile Data Set for Download or QSAR
Report error Found 126 Enz. Inhib. hit(s) with all data for entry = 1978
TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349937BDBM349937(5-(4-((2S,5S)-2-(4-chlorobenzyl)-4,5-dimethylpiper...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349934BDBM349934((R)-5-(4-(2-(4-chlorobenzyl)pyrrolidin-1-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349934BDBM349934((R)-5-(4-(2-(4-chlorobenzyl)pyrrolidin-1-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349942BDBM349942(5-(4-((2S,5S)-2-(4-chlorobenzyl)-5-(cyclohexylmeth...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349941BDBM349941(5-(4-((2S,5S)-2,5-bis(4-chlorobenzyl)-4-methylpipe...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349943BDBM349943(5-(4-((2S,5S)-2-(4-chlorobenzyl)-5-isobutyl-4-meth...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349956BDBM349956(5-(4-((2S,4S)-2-(4-chlorobenzyl)-4-methoxypyrrolid...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349956BDBM349956(5-(4-((2S,4S)-2-(4-chlorobenzyl)-4-methoxypyrrolid...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349950BDBM349950(methyl 2-((2S,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349951BDBM349951(2-((2S,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349961BDBM349961(3-(4-((2S,4R)-2-(4-chlorobenzyl)-4-methoxypyrrolid...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349961BDBM349961(3-(4-((2S,4R)-2-(4-chlorobenzyl)-4-methoxypyrrolid...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349958BDBM349958((5S)-1-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperidin...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349957BDBM349957((3S,5S)-1-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349957BDBM349957((3S,5S)-1-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349960BDBM349960((3R,5S)-1-(1-(5-amino-1H-1,2,4-triazol-3-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349960BDBM349960((3R,5S)-1-(1-(5-amino-1H-1,2,4-triazol-3-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349959BDBM349959(5-(4-((3S,8aS)-3-(4-chlorobenzyl)hexahydropyrrolo[...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349970BDBM349970((S)-5-(4-(3-(4-chlorobenzyl)-7-fluoro-2,3-dihydrob...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349969BDBM349969((S)-5-(4-(3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349972BDBM349972((S)-5-(4-(7,9-dichloro-3-(4-chlorobenzyl)-2,3-dihy...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349971BDBM349971((S)-5-(4-(7-chloro-3-(4-chlorobenzyl)-2,3-dihydrob...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349965BDBM349965((S)-5-(4-(3-(4-chlorobenzyl)-6-methylene-1,4-oxaze...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349968BDBM349968((S)-5-(4-(7-chloro-3-(4-chlorobenzyl)-1-methyl-2,3...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349967BDBM349967((S)-5-(4-(3-(4-chlorobenzyl)-1-methyl-2,3-dihydro-...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349914BDBM349914(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholin...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349914BDBM349914(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholin...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349913BDBM349913((S)-5-(4-(3-(4-bromobenzyl)morpholino)piperidin-1-...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349913BDBM349913((S)-5-(4-(3-(4-bromobenzyl)morpholino)piperidin-1-...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349916BDBM349916(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-isopropylmorpho...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349916BDBM349916(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-isopropylmorpho...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349915BDBM349915(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-ethylmorpholino...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349915BDBM349915(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-ethylmorpholino...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349973BDBM349973((S)-5-(4-(3-(4-chlorobenzyl)-2,3-dihydropyrido[4,3...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349911BDBM349911((S)-5-(4-(3-(4- chlorobenzyl)morpholino) piperidin...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349911BDBM349911((S)-5-(4-(3-(4- chlorobenzyl)morpholino) piperidin...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349911BDBM349911((S)-5-(4-(3-(4- chlorobenzyl)morpholino) piperidin...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349922BDBM349922((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349922BDBM349922((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349921BDBM349921(5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(ethoxymethyl)m...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349921BDBM349921(5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(ethoxymethyl)m...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349924BDBM349924(5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(2-methoxypropa...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349924BDBM349924(5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(2-methoxypropa...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349923BDBM349923(2-((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349923BDBM349923(2-((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349917BDBM349917(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-isobutylmorphol...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349917BDBM349917(5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-isobutylmorphol...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349920BDBM349920(5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(methoxymethyl)...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349920BDBM349920(5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(methoxymethyl)...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 349919BDBM349919((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

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