Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 2476
TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367665BDBM367665(US10227314, Example 4 | (S)-1-(1H-1,2,4-triazol-5-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367664BDBM367664(US10227314, Example 3 | (S)-3-(1-aminobut-3-ynyl)-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367663BDBM367663(US10227314, Example 2 | (S)-1-(1H-tetrazol-5-yl-bu...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367672BDBM367672(US10227314, Compound (S)-2-aminopent-4-ynoic acid)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367671BDBM367671(US10227314, Compound 2-aminopent-4-ynoic acid)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367674BDBM367674(US10227314, Compound 2-amino-3-cyanopropanoic acid)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367662BDBM367662(US10227314, Example 1 | 3-amino-3-(1H-tetrazol-5-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367667BDBM367667(US10227314, Example 6 | (S)-5-(1-aminobut-3-ynyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367666BDBM367666(US10227314, Example 5 | (S)-1-(3-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367673BDBM367673(US10227314, Compound (R)-2-aminopent-4-ynoic acid)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367669BDBM367669(US10227314, Example 8 | (S)-2-amino-N-(phenylsulfo...)
Affinity DataIC50: 1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367668BDBM367668(US10227314, Example 7 | (S)-2-amino-N-(2H-tetrazol...)
Affinity DataIC50: 1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 367670BDBM367670(US10227314, Example 9 | (S)-2-amino-N-(methylsulfo...)
Affinity DataIC50: 1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent