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Found 13 Enz. Inhib. hit(s) with all data for entry = 2476
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367663((S)-1-(1H-tetrazol-5-yl-but-3-ynylamine hydrochlor...)
Affinity DataIC50: <2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367664((S)-3-(1-aminobut-3-ynyl)-1,2,4-oxadiazol-5(4H)-on...)
Affinity DataIC50: <2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367674(US10227314, Compound 2-amino-3-cyanopropanoic acid)
Affinity DataIC50: <2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367665((S)-1-(1H-1,2,4-triazol-5-yl)but-3-yn-1-amine hydr...)
Affinity DataIC50: <2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367671(US10227314, Compound 2-aminopent-4-ynoic acid)
Affinity DataIC50: <2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367672(US10227314, Compound (S)-2-aminopent-4-ynoic acid)
Affinity DataIC50: <2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367662(3-amino-3-(1H-tetrazol-5-yl)propionitrile dihydroc...)
Affinity DataIC50: >1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367667((S)-5-(1-aminobut-3-ynyl)-1H-1,2,4-triazol-3-amine...)
Affinity DataIC50: >1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367673(US10227314, Compound (R)-2-aminopent-4-ynoic acid)
Affinity DataIC50: >1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367666((S)-1-(3-(trifluoromethyl)-1H-1,2,4-triazol-5-yObu...)
Affinity DataIC50: >1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367670((S)-2-amino-N-(methylsulfonyl)pent-4-ynamide hydro...)
Affinity DataIC50:  1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367669((S)-2-amino-N-(phenylsulfonyl)pent-4-ynamide hydro...)
Affinity DataIC50:  1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystathionine gamma-lyase(Homo sapiens (Human))
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367668((S)-2-amino-N-(2H-tetrazol-5-yl)pent-4-ynamide | ...)
Affinity DataIC50:  1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails US Patent