Compile Data Set for Download or QSAR
Report error Found 161 Enz. Inhib. hit(s) with all data for entry = 2512
TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369539BDBM369539(US10233152, Example 64)
Affinity DataIC50: 0.900nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369535BDBM369535(US10233152, Example 60)
Affinity DataIC50: 1nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369495BDBM369495(US10233152, Example 33)
Affinity DataIC50: 1nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369532BDBM369532(US10233152, Example 57)
Affinity DataIC50: 2nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369621BDBM369621(US10233152, Example 128)
Affinity DataIC50: 2nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369533BDBM369533(US10233152, Example 58)
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369484BDBM369484(US10233152, Example 24)
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369650BDBM369650(US10233152, Example 157)
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369478BDBM369478(N,N-Dimethyl-2-(4-(2-(4-(((1R,2S)-2-phenylcyclopro...)
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369496BDBM369496(US10233152, Example 34)
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369512BDBM369512(US10233152, Example 50)
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369576BDBM369576(US10233152, Example 91)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369551BDBM369551(US10233152, Example 74)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369574BDBM369574(US10233152, Example 89)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369491BDBM369491(US10233152, Example 29)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369541BDBM369541(US10233152, Example 66)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369476BDBM369476(N-(Methylsulfonyl)-2-(4-(2-(4-(((1R,2S)-2-phenylcy...)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369483BDBM369483(US10233152, Example 23)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369530BDBM369530(US10233152, Example 55)
Affinity DataIC50: 4nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369550BDBM369550(US10233152, Example 73)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369531BDBM369531(US10233152, Example 56)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369593BDBM369593(US10233152, Example 104)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369580BDBM369580(US10233152, Example 95)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369472BDBM369472(1-[2-(4-bromophenoxy)ethyl]-N-[(1R,2S)-2-phenylcyc...)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369482BDBM369482(US10233152, Example 22)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369643BDBM369643(US10233152, Example 150)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369481BDBM369481(US10233152, Example 21)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369480BDBM369480(1-[2-(4-morpholinophenoxy)ethyl]-N—[(R, 2S)-2...)
Affinity DataIC50: 5nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369594BDBM369594(US10233152, Example 105)
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369513BDBM369513(US10233152, Example 51)
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369570BDBM369570(US10233152, Example 85)
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369514BDBM369514(US10233152, Example 52)
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369545BDBM369545(US10233152, Example 68)
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369630BDBM369630(US10233152, Example 137)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369602BDBM369602(US10233152, Example 111)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369561BDBM369561(US10233152, Example 78)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369478BDBM369478(N,N-Dimethyl-2-(4-(2-(4-(((1R,2S)-2-phenylcyclopro...)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369476BDBM369476(N-(Methylsulfonyl)-2-(4-(2-(4-(((1R,2S)-2-phenylcy...)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369529BDBM369529(US10233152, Example 54)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369571BDBM369571(US10233152, Example 86)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369534BDBM369534(US10233152, Example 59)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369557BDBM369557(US10233152, Example 123 | US10233152, Example 76)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369470BDBM369470((trans)-N-[[1-(2-phenoxyethyl)azetidin-3-yl]methyl...)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369537BDBM369537(US10233152, Example 62)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369651BDBM369651(US10233152, Example 158)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369490BDBM369490(US10233152, Example 28)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369544BDBM369544(US10233152, Example 67)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369639BDBM369639(US10233152, Example 146)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369540BDBM369540(US10233152, Example 65)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369547BDBM369547(US10233152, Example 70)
Affinity DataIC50: 8nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

Displayed 1 to 50 (of 161 total ) | Next | Last >>
Jump to: