Compile Data Set for Download or QSAR
Report error Found 160 Enz. Inhib. hit(s) with all data for entry = 2539
TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370456BDBM370456(1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370480BDBM370480(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1- (fu...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370479BDBM370479(1-(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol- 5-yl...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370478BDBM370478(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(thiazol-5- y...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370466BDBM370466(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1- (1,...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370465BDBM370465(1-cyclohexyl-2-(8-fluoro-5H-imidazo[5,1- a]isoindo...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370472BDBM370472(1-(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol- 5-yl...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 50138830BDBM50138830(CHEMBL3752659 | US10233190, Example 1415)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370483BDBM370483(1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl)pr...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370508BDBM370508(1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370509BDBM370509(4-(1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370500BDBM370500(1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- ylide...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 50138829BDBM50138829(CHEMBL3754097 | US10233190, Example 1416)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370522BDBM370522((2S)-1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol- 5-...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370528BDBM370528((2S)-2-amino-1-(4-(1-hydroxy-2-(5H- imidazo[5,1-a]...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370527BDBM370527((4-fluorophenyl)(4-(1-hydroxy-2-(5H- imidazo[5,1-a...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370516BDBM370516(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370513BDBM370513(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370537BDBM370537(tert-butyl 4-((R)-1-hydroxy-2-((R)-5H- imidazo[5,1...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370544BDBM370544(US10233190, Example 1477 | 4-((R)-1-hydroxy-2-((R)...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370543BDBM370543(US10233190, Example 1476 | 4-((S)-1-hydroxy-2-((R)...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370541BDBM370541(US10233190, Example 1474 | 2-(5H-imidazo[5,1-a]iso...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370536BDBM370536(tert-butyl 4-((S)-1-hydroxy-2-((R)-5H- imidazo[5,1...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370428BDBM370428(tert-butyl (4-(2-(5H-imidazo[5,1-a]isoindol-5- yl)...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370556BDBM370556(US10233190, Example 1489 | (1R,4r)-4-((R)-2-((R)-6...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370426BDBM370426(2-(5H-imidazo[5,1-a]isoindol-5-yl)ethyl 2- (((1R,2...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370554BDBM370554(US10233190, Example 1487 | (1S,4r)-4-((S)-2-((R)-6...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370425BDBM370425(2-(6-chloro-5H-imidazo[5,1-a]isoindol-5-yl)-1- cyc...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370560BDBM370560(US10233190, Example 1493 | 1-(4-((S)-1-hydroxy-2-(...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370558BDBM370558(US10233190, Example 1491 | 1-(4-((R)-1-hydroxy-2-(...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370420BDBM370420(ethyl 2-(5H-imidazo[5,1-a]isoindol-5-yl)acetate | ...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370419BDBM370419(2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol | US1023...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370550BDBM370550(US10233190, Example 1483 | (1S,4s)-4-((R)-2-((R)-6...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370549BDBM370549(US10233190, Example 1482 | (1R,4s)-4-((S)-2-((R)-6...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370442BDBM370442(1-(5H-imidazo[5,1-a]isoindol-5-yl)-2- methylpropan...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370441BDBM370441(1-(2-chlorophenyl)-2-(5H-imidazo[5,1- a]isoindol-5...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370569BDBM370569(US10233190, Example 1502 | 2-(5H-imidazo[5,1-a]iso...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370448BDBM370448(1-(3-chlorophenyl)-2-(5H-imidazo[5,1- a]isoindol-5...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370447BDBM370447(1-(2,4-dimethylfuran-3-yl)-2-(6-fluoro-5H- imidazo...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370445BDBM370445(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1- phenylethano...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370435BDBM370435(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(2- nitrophen...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370433BDBM370433(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(3- nitrophen...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370439BDBM370439(1-(2-aminophenyl)-2-(5H-imidazo[5,1- a]isoindol-5-...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370438BDBM370438(tert-butyl (2-(1-hydroxy-2-(5H-imidazo[5,1- a]isoi...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370437BDBM370437(tert-butyl (2-(2-(5H-imidazo[5,1-a]isoindol-5- yl)...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370458BDBM370458(1-(3-aminophenyl)-2-(5H-imidazo[5,1- a]isoindol-5-...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370457BDBM370457(tert-butyl (3-(1-hydroxy-2-(5H-imidazo[5,1- a]isoi...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370464BDBM370464(1-(cyclohex-1-en-1-yl)-2-(5H-imidazo[5,1- a]isoind...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 370463BDBM370463(2-(8-chloro-5H-imidazo[5,1-a]isoindol-5-yl)-1- cyc...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 50138818BDBM50138818(CHEMBL3754460 | US10233190, Example 1356)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

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