Compile Data Set for Download or QSAR
Report error Found 98 Enz. Inhib. hit(s) with all data for entry = 2544
TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370640BDBM370640(US10238743, Example 16)
Affinity DataKi:  1nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370635BDBM370635(US10238743, Example 11)
Affinity DataKi:  2nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370635BDBM370635(US10238743, Example 11)
Affinity DataKi:  2nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370637BDBM370637(US10238743, Example 13)
Affinity DataKi:  4nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370661BDBM370661(US10238743, Example 36)
Affinity DataKi:  4nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370637BDBM370637(US10238743, Example 13)
Affinity DataKi:  4nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370644BDBM370644(US10238743, Example 20)
Affinity DataKi:  5nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370636BDBM370636(US10238743, Example 12)
Affinity DataKi:  5nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370649BDBM370649(US10238743, Example 25)
Affinity DataKi:  5nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370638BDBM370638(US10238743, Example 14)
Affinity DataKi:  6nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370639BDBM370639(US10238743, Example 15)
Affinity DataKi:  6nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370653BDBM370653(US10238743, Example 28)
Affinity DataKi:  7nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370647BDBM370647(US10238743, Example 23)
Affinity DataKi:  7nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370649BDBM370649(US10238743, Example 25)
Affinity DataKi:  7nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370647BDBM370647(US10238743, Example 23)
Affinity DataKi:  7nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370643BDBM370643(US10238743, Example 19)
Affinity DataKi:  8nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370651BDBM370651(US10238743, Example 27)
Affinity DataKi:  10nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370660BDBM370660(US10238743, Example 35)
Affinity DataKi:  10nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370639BDBM370639(US10238743, Example 15)
Affinity DataKi:  10nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370646BDBM370646(US10238743, Example 22)
Affinity DataKi:  10nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370655BDBM370655(US10238743, Example 30)
Affinity DataKi:  10nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370638BDBM370638(US10238743, Example 14)
Affinity DataKi:  10nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370656BDBM370656(US10238743, Example 31)
Affinity DataKi:  10nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370650BDBM370650(US10238743, Example 26)
Affinity DataKi:  10nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370642BDBM370642(US10238743, Example 18)
Affinity DataKi:  11nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370654BDBM370654(US10238743, Example 29)
Affinity DataKi:  14nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370640BDBM370640(US10238743, Example 16)
Affinity DataKi:  14nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370634BDBM370634(US10238743, Example 10)
Affinity DataKi:  15nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370641BDBM370641(US10238743, Example 17)
Affinity DataKi:  16nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370659BDBM370659(US10238743, Example 34)
Affinity DataKi:  17nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370653BDBM370653(US10238743, Example 28)
Affinity DataKi:  18nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370641BDBM370641(US10238743, Example 17)
Affinity DataKi:  18nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370651BDBM370651(US10238743, Example 27)
Affinity DataKi:  18nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370650BDBM370650(US10238743, Example 26)
Affinity DataKi:  18nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370656BDBM370656(US10238743, Example 31)
Affinity DataKi:  19nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370660BDBM370660(US10238743, Example 35)
Affinity DataKi:  19nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370661BDBM370661(US10238743, Example 36)
Affinity DataKi:  25nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370628BDBM370628(US10238743, Example 6)
Affinity DataKi:  25nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370657BDBM370657(US10238743, Example 32)
Affinity DataKi:  27nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370645BDBM370645(US10238743, Example 21)
Affinity DataKi:  34nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370657BDBM370657(US10238743, Example 32)
Affinity DataKi:  34nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370634BDBM370634(US10238743, Example 10)
Affinity DataKi:  35nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370644BDBM370644(US10238743, Example 20)
Affinity DataKi:  36nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370645BDBM370645(US10238743, Example 21)
Affinity DataKi:  45nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370669BDBM370669(US10238743, Example 44)
Affinity DataKi:  45nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370627BDBM370627(US10238743, Example 5)
Affinity DataKi:  47nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370658BDBM370658(US10238743, Example 33)
Affinity DataKi:  48nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370659BDBM370659(US10238743, Example 34)
Affinity DataKi:  52nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370668BDBM370668(US10238743, Example 43)
Affinity DataKi:  57nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 370636BDBM370636(US10238743, Example 12)
Affinity DataKi:  58nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

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