Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 2548
TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370883BDBM370883(US10239840, Example 13)
Affinity DataIC50: 4nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370878BDBM370878(US10239840, Example 8)
Affinity DataIC50: 4nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370877BDBM370877(US10239840, Example 7)
Affinity DataIC50: 5nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370875BDBM370875(US10239840, Example 5)
Affinity DataIC50: 5nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370880BDBM370880(US10239840, Example 10)
Affinity DataIC50: 5nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370892BDBM370892(US10239840, Example 21)
Affinity DataIC50: 8nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370893BDBM370893(US10239840, Example 22)
Affinity DataIC50: 9nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370881BDBM370881(US10239840, Example 11)
Affinity DataIC50: 9nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370888BDBM370888(US10239840, Example 17)
Affinity DataIC50: 10nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370889BDBM370889(US10239840, Example 18)
Affinity DataIC50: 13nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370886BDBM370886(US10239840, Example 16)
Affinity DataIC50: 13nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370879BDBM370879(US10239840, Example 9)
Affinity DataIC50: 14nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370884BDBM370884(US10239840, Example 14)
Affinity DataIC50: 17nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370882BDBM370882(US10239840, Example 12)
Affinity DataIC50: 19nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370871BDBM370871(US10239840, Example 1)
Affinity DataIC50: 27nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370874BDBM370874(US10239840, Example 4)
Affinity DataIC50: 34nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370891BDBM370891(US10239840, Example 20)
Affinity DataIC50: 42nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370876BDBM370876(US10239840, Example 6)
Affinity DataIC50: 60nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370872BDBM370872(US10239840, Example 2)
Affinity DataIC50: 76nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370885BDBM370885(US10239840, Example 15)
Affinity DataIC50: 77nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370890BDBM370890(US10239840, Example 19)
Affinity DataIC50: 92nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

TargetProtein Tax-1(HTLV-1)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 370873BDBM370873(US10239840, Example 3)
Affinity DataIC50: 219nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent