Compile Data Set for Download or QSAR
Report error Found 1854 Enz. Inhib. hit(s) with all data for entry = 2659
TargetSerine/threonine-protein kinase TBK1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 277982BDBM277982(2-((2R,4R)-4-hydroxy-2-methylpyrrolidin-1-yl)-5-(4...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278238BDBM278238(2-(((S)-3,3-difluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278323BDBM278323(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 277810BDBM277810(5-(4-((4-(4-acetylpiperazin-1-yl)-3-methoxyphenyl)...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 277983BDBM277983(2-((2S,4R)-4-hydroxy-2-methylpyrrolidin-1-yl)-5-(4...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278074BDBM278074(2-(((3R,4S)-3-fluoro-1-formylpiperidin-4-yl)oxy)-5...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 375573BDBM375573(5-(4-((3-fluoro-4-(piperazin-1-yl)phenyl)amino)-1,...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278247BDBM278247(2-(((S)-3,3-difluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278161BDBM278161(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278080BDBM278080((S)-2-((1-acetyl-3,3-difluoropiperidin-4-yl)oxy)-5...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278167BDBM278167(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278338BDBM278338((S)-2-((3,3-difluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 277996BDBM277996(US10040781, Example 218 | 2-((cis-3-fluoro-1-(2-hy...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278081BDBM278081((S)-2-((3,3-difluoro-1-formylpiperidin-4-yl)oxy)-5...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 278081BDBM278081((S)-2-((3,3-difluoro-1-formylpiperidin-4-yl)oxy)-5...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278162BDBM278162(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278333BDBM278333(2-(((3R,4S)-1-((S)-2,3-dihydroxypropanoyl)-3-fluor...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278079BDBM278079((S)-2-((1-acetyl-3,3-difluoropiperidin-4-yl)oxy)-5...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278171BDBM278171(5-(4-((3-(difluoromethoxy)-4-(4-(oxetan-3-yl)piper...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278085BDBM278085(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278256BDBM278256((3R,4S)-4-(2-cyano-4-(4-((4-(4-(oxetan-3-yl)pipera...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278170BDBM278170(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278087BDBM278087(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278172BDBM278172(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278086BDBM278086(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278257BDBM278257(2-(((S)-1-((S)-2,3-dihydroxypropanoyl)-3,3-difluor...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278083BDBM278083(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278339BDBM278339(2-(((S)-3,3-difluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278082BDBM278082((S)-2-((3,3-difluoro-1-formylpiperidin-4-yl)oxy)-5...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278015BDBM278015(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 278006BDBM278006(2-((3,3-difluoro-1-((S)-2-hydroxypropanoyl)piperid...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278176BDBM278176(2-(((3R,4S)-1-((S)-2,3-dihydroxypropanoyl)-3-fluor...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278007BDBM278007(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 278007BDBM278007(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278092BDBM278092(4-(4-((4-(3-cyano-4-(((3R,4S)-3-fluoro-1-((S)-2-hy...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278263BDBM278263(2-(((3R,4S)-3-fluoro-1-(1-methyl-1H-1,2,3-triazole...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 277921BDBM277921(2-(((3R,4S)-3-fluoro-1-(1H-1,2,3-triazole-5-carbon...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278173BDBM278173(5-(4-((3-(difluoromethoxy)-4-(4-(oxetan-3-yl)piper...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278089BDBM278089(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278174BDBM278174(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278011BDBM278011(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278096BDBM278096(2-(((3R,4S)-3-fluoro-1-(1H-pyrazole-5-carbonyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278267BDBM278267(2-(((3R,4S)-3-fluoro-1-(2-methoxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 277925BDBM277925(2-(((3R,4S)-3-fluoro-1-(1-methyl-1H-1,2,3-triazole...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278010BDBM278010(2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278268BDBM278268(2-(((3R,4S)-3-fluoro-1-(5-methyl-4H-1,2,4-triazole...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278353BDBM278353(2-(((3R,4S)-1-((S)-2,3-dihydroxypropanoyl)-3-fluor...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 277923BDBM277923(2-(((3R,4S)-3-fluoro-1-(1H-pyrazole-5-carbonyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 277922BDBM277922(2-(((3R,4S)-3-fluoro-1-(4H-1,2,4-triazole-3-carbon...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 278178BDBM278178(2-(((3R,4S)-3-fluoro-1-((S)-2-hydroxypropanoyl)pip...)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

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