Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 2818
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362044(US9833448, Example 4 | US10272077, Example 4)
Affinity DataKi:  0.0150nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362171(US9833448, Example 5 | US10272077, Example 5)
Affinity DataKi:  0.0170nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM381649(US10272077, Example 17)
Affinity DataKi:  0.0550nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361594(US9833448, Example 1 | US10272077, Example 1)
Affinity DataKi:  0.0670nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361595(US9833448, Example 3 | US10272077, Example 3)
Affinity DataKi:  0.0670nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362175(US9833448, Example 26 | US10272077, Example 26)
Affinity DataKi:  0.0930nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362176(US9833448, Example 30 | US10272077, Example 30)
Affinity DataKi:  0.140nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362177(US9833448, Example 31 | US10272077, Example 31)
Affinity DataKi:  0.170nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362172(US9833448, Example 6 | US10272077, Example 6)
Affinity DataKi:  0.210nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362173(US9833448, Example 11 | US10272077, Example 11)
Affinity DataKi:  0.25nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362180(US9833448, Example 10 from U.S. Pat. No. 7,390,798...)
Affinity DataKi:  1.70nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362179(US9833448, Example 9 from U.S. Pat. No. 7,390,798 ...)
Affinity DataKi:  1.90nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362181(US9833448, Example 8 from US 2010/0179166 | US1027...)
Affinity DataKi:  4.30nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM362178(US9833448, Example 8 from U.S. Pat. No. 7,390,798 ...)
Affinity DataKi:  7.40nMAssay Description:The binding of 125I-CGRP to receptors in SK-N-MC cell membranes was carried out essentially as described (Edvinsson et al. (2001) Eur. J. Pharmacol. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
Go to US Patent