Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 2882
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384097BDBM384097(US10280167, Example 26)
Affinity DataEC50:  5nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384096BDBM384096(US10280167, Example 25)
Affinity DataEC50:  6nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384113BDBM384113(US10280167, Example 60)
Affinity DataEC50:  34nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384095BDBM384095(US10280167, Example 24)
Affinity DataEC50:  46nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384107BDBM384107(US10280167, Example 36)
Affinity DataEC50:  47nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384086BDBM384086(US10280167, Example 9)
Affinity DataEC50:  50nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384109BDBM384109(US10280167, Example 54)
Affinity DataEC50:  50nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384083BDBM384083(US10280167, Example 6)
Affinity DataEC50:  53nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384078BDBM384078(US10280167, Example 1)
Affinity DataEC50:  81nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384094BDBM384094(US10280167, Example 23)
Affinity DataEC50:  130nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384081BDBM384081(US10280167, Example 4)
Affinity DataEC50:  160nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384085BDBM384085(US10280167, Example 8)
Affinity DataEC50:  170nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384101BDBM384101(US10280167, Example 30)
Affinity DataEC50:  170nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384106BDBM384106(US10280167, Example 35)
Affinity DataEC50:  170nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384082BDBM384082(US10280167, Example 5)
Affinity DataEC50:  200nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384088BDBM384088(US10280167, Example 11)
Affinity DataEC50:  330nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384079BDBM384079(US10280167, Example 2)
Affinity DataEC50:  531nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384089BDBM384089(US10280167, Example 12)
Affinity DataEC50:  590nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384084BDBM384084(US10280167, Example 7)
Affinity DataEC50:  640nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384093BDBM384093(US10280167, Example 20)
Affinity DataEC50:  680nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384105BDBM384105(US10280167, Example 34)
Affinity DataEC50:  690nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384115BDBM384115(US10280167, Example 62)
Affinity DataEC50:  700nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384087BDBM384087(US10280167, Example 10)
Affinity DataEC50:  730nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384108BDBM384108(US10280167, Example 53)
Affinity DataEC50:  760nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384098BDBM384098(US10280167, Example 27)
Affinity DataEC50:  800nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384104BDBM384104(US10280167, Example 33)
Affinity DataEC50:  810nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384111BDBM384111(US10280167, Example 57)
Affinity DataEC50:  1.21E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384110BDBM384110(US10280167, Example 55)
Affinity DataEC50:  1.27E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384102BDBM384102(US10280167, Example 31)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384114BDBM384114(US10280167, Example 61)
Affinity DataEC50:  1.34E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384103BDBM384103(US10280167, Example 32)
Affinity DataEC50:  1.51E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384100BDBM384100(US10280167, Example 29)
Affinity DataEC50:  1.66E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384091BDBM384091(US10280167, Example 18)
Affinity DataEC50:  2.58E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384112BDBM384112(US10280167, Example 58)
Affinity DataEC50:  2.75E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384116BDBM384116(US10280167, Example 63)
Affinity DataEC50:  6.72E+3nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384092BDBM384092(US10280167, Example 19)
Affinity DataEC50:  1.24E+4nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384080BDBM384080(US10280167, Example 3)
Affinity DataEC50:  1.40E+4nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384090BDBM384090(US10280167, Example 15)
Affinity DataEC50:  1.69E+4nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 384099BDBM384099(US10280167, Example 28)
Affinity DataEC50: >2.38E+4nMAssay Description:Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent