Compile Data Set for Download or QSAR
Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 2988
TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387758BDBM387758(US10294214, Example 58)
Affinity DataEC50:  79.4nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387703BDBM387703(methyl 3-(2-(4-cyclohexylpiperidin-1-yl)acetamido)...)
Affinity DataEC50:  200nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387759BDBM387759(US10294214, Example 59)
Affinity DataEC50:  200nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387763BDBM387763(US10294214, Example 63)
Affinity DataEC50:  200nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387760BDBM387760(US10294214, Example 60)
Affinity DataEC50:  200nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387766BDBM387766(US10294214, Example 66)
Affinity DataEC50:  251nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387764BDBM387764(US10294214, Example 64)
Affinity DataEC50:  251nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387739BDBM387739(US10294214, Example 39)
Affinity DataEC50:  251nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387738BDBM387738(US10294214, Example 38)
Affinity DataEC50:  251nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387737BDBM387737(US10294214, Example 37)
Affinity DataEC50:  251nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387762BDBM387762(US10294214, Example 62)
Affinity DataEC50:  251nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387761BDBM387761(US10294214, Example 61)
Affinity DataEC50:  251nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387767BDBM387767(US10294214, Example 67)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387765BDBM387765(US10294214, Example 65)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387705BDBM387705(US10294214, Example 5)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387704BDBM387704(US10294214, Example 4)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387711BDBM387711(US10294214, Example 11)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387742BDBM387742(US10294214, Example 42)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387710BDBM387710(US10294214, Example 10)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387740BDBM387740(US10294214, Example 40)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387708BDBM387708(US10294214, Example 8)
Affinity DataEC50:  316nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387771BDBM387771(US10294214, Example 71)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387707BDBM387707(US10294214, Example 7)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387770BDBM387770(US10294214, Example 70)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387706BDBM387706(US10294214, Example 6)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387768BDBM387768(US10294214, Example 68)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387743BDBM387743(US10294214, Example 43)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387741BDBM387741(US10294214, Example 41)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387709BDBM387709(US10294214, Example 9)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387744BDBM387744(US10294214, Example 44)
Affinity DataEC50:  398nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387702BDBM387702(N-(2-(cyclopropanecarbonyl)-1H-indol-3-yl)-2-(8-az...)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387748BDBM387748(US10294214, Example 48)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387769BDBM387769(US10294214, Example 69)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387772BDBM387772(US10294214, Example 72)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387746BDBM387746(US10294214, Example 46)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387745BDBM387745(US10294214, Example 45)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387713BDBM387713(US10294214, Example 13)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387712BDBM387712(US10294214, Example 12)
Affinity DataEC50:  501nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387719BDBM387719(US10294214, Example 19)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387749BDBM387749(US10294214, Example 49)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387717BDBM387717(US10294214, Example 17)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387716BDBM387716(US10294214, Example 16)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387722BDBM387722(US10294214, Example 22)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387721BDBM387721(US10294214, Example 21)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387720BDBM387720(US10294214, Example 20)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387774BDBM387774(US10294214, Example 74)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387773BDBM387773(US10294214, Example 73)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387747BDBM387747(US10294214, Example 47)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387715BDBM387715(US10294214, Example 15)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 387714BDBM387714(US10294214, Example 14)
Affinity DataEC50:  631nMAssay Description:Analysis of pharmacological properties of compounds was performed using the LANCE cAMP kit (Perkin Elmer). HEK293 cells stably expressing the hMC4R w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

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