Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 3250
Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349633(2-(4-Chlorophenyl)-2-(1-((3,5-dimethyl-1H-pyrazol-...)
Affinity DataIC50: 40nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349645(2-(4-Chlorophenyl)-2-(1-((1,3,5-trimethyl-1H-pyraz...)
Affinity DataIC50: 40nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349636(2-(4-Chlorophenyl)-2-(1-((3,5-diethyl-1H-pyrazol-4...)
Affinity DataIC50: 50nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349653(3-((1-(3,5-Dimethyl-1H-pyrazol-4-yl)sulfonyl)piper...)
Affinity DataIC50: 60nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349639(2-(1-((3,5-Dimethyl-1H-pyrazol-4-yl)sulfonyl)piper...)
Affinity DataIC50: 150nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349646(4-((4-Chlorophenyl)fluoromethylene)-1-((3,5-dimeth...)
Affinity DataIC50: 160nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349635(2-(4-Chloro-2-fluorophenyl)-2-(1-((3,5-dimethyl-1H...)
Affinity DataIC50: 180nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349650(4-((4-Chloro-3-fluorophenyl)fluoromethylene)-1-((3...)
Affinity DataIC50: 190nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349637(2-(4-Chlorophenyl)-2-(1-((1,5-dimethyl-3-(trifluor...)
Affinity DataIC50: 210nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349648(4-((2,4-Dichlorophenyl)fluoromethylene)-1-((3,5-di...)
Affinity DataIC50: 260nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349651(4-((4-Chloro-2-fluorophenyl)fluoromethylene)-1-((3...)
Affinity DataIC50: 400nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349640(2-(4-Chlorophenyl)-2-(1-((3,5-dimethyl-1H-pyrazol-...)
Affinity DataIC50: 470nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349649(4-((3,4-Dichlorophenyl)fluoromethylene)-1-((3,5-di...)
Affinity DataIC50: 520nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349642(4-(4-Chloro-2-fluorobenzylidene)-1-((1,3,5-trimeth...)
Affinity DataIC50: 550nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349641(4-(4-Chloro-2-fluorobenzylidene)-1-((3,5-dimethyl-...)
Affinity DataIC50: 600nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349644(4-(4-Chlorobenzylidene)-1-((3,5-dimethyl-1H-pyrazo...)
Affinity DataIC50: 760nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349643(4-(1-(4-Chlorophenypethylidene)-1-((3,5-dimethyl-1...)
Affinity DataIC50: 760nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349631(4-(4-Chloro-3-fluorobenzyl)-1-((3-cyclopropyl-5-me...)
Affinity DataIC50: 1.37E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349652(4-((2,4-Difluorophenyl)fluoromethylene)-1-(3,5-dim...)
Affinity DataIC50: 1.63E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349647(4-((3-Chloro-4-fluorophenyl)fluoromethylene)-1-((3...)
Affinity DataIC50: 1.88E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349632(Methyl 2-(4-Chlorophenyl)-2-(1-((3,5-dimethyl-1H-p...)
Affinity DataIC50: 3.10E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349634(2-(2,6-Difluorophenyl)-2-(1-((3,5-dimethyl-1H-pyra...)
Affinity DataIC50: 3.68E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM349638(2-(2,6-Difluorophenyl)-2-(1-((1,3,5-trimethyl-1H-p...)
Affinity DataIC50: 5.43E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent