Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 3515
TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402431BDBM402431(US10329291, Example 22)
Affinity DataKi:  0.5nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271168BDBM50271168(CHEMBL4127283)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402420BDBM402420(US10329291, Example 11)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271163BDBM50271163(CHEMBL4129654)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402345BDBM402345(US10329291, Example 1)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271175BDBM50271175(CHEMBL4126365)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402432BDBM402432(US10329291, Example 23)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271172BDBM50271172(CHEMBL4127711)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402422BDBM402422(US10329291, Example 13)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402422BDBM402422(US10329291, Example 13)
Affinity DataKi:  1nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402427BDBM402427(US10329291, Example 18)
Affinity DataKi:  3nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402424BDBM402424(US10329291, Example 15)
Affinity DataKi:  3nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271167BDBM50271167(CHEMBL4127870)
Affinity DataKi:  3nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271172BDBM50271172(CHEMBL4127711)
Affinity DataKi:  3nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271173BDBM50271173(CHEMBL4129113)
Affinity DataKi:  3nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271166BDBM50271166(CHEMBL4130055)
Affinity DataKi:  4nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271163BDBM50271163(CHEMBL4129654)
Affinity DataKi:  4nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402431BDBM402431(US10329291, Example 22)
Affinity DataKi:  4nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271173BDBM50271173(CHEMBL4129113)
Affinity DataKi:  4nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271166BDBM50271166(CHEMBL4130055)
Affinity DataKi:  6nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402432BDBM402432(US10329291, Example 23)
Affinity DataKi:  6nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271171BDBM50271171(CHEMBL4125904)
Affinity DataKi:  6nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402425BDBM402425(US10329291, Example 16)
Affinity DataKi:  7nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402426BDBM402426(US10329291, Example 17)
Affinity DataKi:  8nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402429BDBM402429(US10329291, Example 20)
Affinity DataKi:  9nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271168BDBM50271168(CHEMBL4127283)
Affinity DataKi:  10nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402428BDBM402428(US10329291, Example 19)
Affinity DataKi:  10nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402345BDBM402345(US10329291, Example 1)
Affinity DataKi:  10nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402426BDBM402426(US10329291, Example 17)
Affinity DataKi:  11nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402420BDBM402420(US10329291, Example 11)
Affinity DataKi:  16nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402434BDBM402434(US10329291, Example 35)
Affinity DataKi:  16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271174BDBM50271174(CHEMBL4126480)
Affinity DataKi:  16nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402424BDBM402424(US10329291, Example 15)
Affinity DataKi:  16nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402427BDBM402427(US10329291, Example 18)
Affinity DataKi:  17nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402346BDBM402346(US10329291, Example 2)
Affinity DataKi:  18nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271175BDBM50271175(CHEMBL4126365)
Affinity DataKi:  22nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271171BDBM50271171(CHEMBL4125904)
Affinity DataKi:  23nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402425BDBM402425(US10329291, Example 16)
Affinity DataKi:  25nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402423BDBM402423(US10329291, Example 14)
Affinity DataKi:  25nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402346BDBM402346(US10329291, Example 2)
Affinity DataKi:  28nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402428BDBM402428(US10329291, Example 19)
Affinity DataKi:  31nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402429BDBM402429(US10329291, Example 20)
Affinity DataKi:  36nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402423BDBM402423(US10329291, Example 14)
Affinity DataKi:  40nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271167BDBM50271167(CHEMBL4127870)
Affinity DataKi:  42nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402435BDBM402435(US10329291, Example 36)
Affinity DataKi:  71nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50271174BDBM50271174(CHEMBL4126480)
Affinity DataKi:  126nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402430BDBM402430(US10329291, Example 21)
Affinity DataKi:  198nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402430BDBM402430(US10329291, Example 21)
Affinity DataKi:  206nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402434BDBM402434(US10329291, Example 35)
Affinity DataKi:  368nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 402435BDBM402435(US10329291, Example 36)
Affinity DataKi:  1.08E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

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