Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 8599
TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406370BDBM406370(N-(tert-Butylsulfonyl)-4-fluoro-2-((3S,4R or 3R,4S...)
Affinity DataEC50:  2nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406401BDBM406401(US10336733, Example 45)
Affinity DataEC50:  3nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406372BDBM406372(N-(Cyclopropylsulfonyl)-4-fluoro-2-((3S,4R or 3R,4...)
Affinity DataEC50:  4nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406365BDBM406365(4-Fluoro-2-((3S,4R or 3R,4S)-4-hydroxy-3-(pyridin-...)
Affinity DataEC50:  4nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406404BDBM406404(N-(tert-Butylsulfonyl)-2-((3S,4R or 3R,4S)-4-hydro...)
Affinity DataEC50:  5nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406358BDBM406358(4-Fluoro-2-((3S,4R or 3R,4S)-4-hydroxy-3-(pyridin-...)
Affinity DataEC50:  6nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406388BDBM406388(US10336733, Example 34 | N-(tert-Butylsulfonyl)-2-...)
Affinity DataEC50:  9nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406396BDBM406396(2-((Rac-trans)-3-([1,1′-Biphenyl]-4-ylmethyl...)
Affinity DataEC50:  9nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406388BDBM406388(US10336733, Example 34 | N-(tert-Butylsulfonyl)-2-...)
Affinity DataEC50:  11nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406396BDBM406396(2-((Rac-trans)-3-([1,1′-Biphenyl]-4-ylmethyl...)
Affinity DataEC50:  11nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406402BDBM406402(2-(Rac-trans)-4-Hydroxy-3-((2-phenyloxazol-4-yl)me...)
Affinity DataEC50:  15nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406378BDBM406378(2-((3S,4R or 3R,4S)-3-Benzyl-4-hydroxychroman-7-yl...)
Affinity DataEC50:  15nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406381BDBM406381(US10336733, Example 25)
Affinity DataEC50:  16nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406368BDBM406368(N-(tert-Butylsulfonyl)-2-((3S,4R or 3R,4S)-4-hydro...)
Affinity DataEC50:  17nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406380BDBM406380(2-((3S,4R or 3R,4S)-3-Benzyl-4-hydroxychroman-7-yl...)
Affinity DataEC50:  17nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406399BDBM406399(US10336733, Example 43)
Affinity DataEC50:  19nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406364BDBM406364(2-((3S,4R or 3R,4S)-4-Hydroxy-3-(pyridin-2-ylmethy...)
Affinity DataEC50:  22nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406374BDBM406374(N-((Cyclopropylmethyl)sulfonyl)-2-((3,4-trans)-4-h...)
Affinity DataEC50:  23nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406373BDBM406373(2-((3,4-trans)-4-Hydroxy-3-(pyridin-2-ylmethyl)chr...)
Affinity DataEC50:  24nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406383BDBM406383(US10336733, Example 27)
Affinity DataEC50:  26nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406362BDBM406362(N-(Cyclopropylsulfonyl)-2-((3S,4R or 3R,4S)-4-hydr...)
Affinity DataEC50:  28nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406398BDBM406398(US10336733, Example 42)
Affinity DataEC50:  35nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406392BDBM406392(US10336733, Example 37 | N-(tert-Butylsulfonyl)-2-...)
Affinity DataEC50:  36nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406395BDBM406395(2-((Rac-cis)-3-([1,1′-Biphenyl]-4-ylmethyl)-...)
Affinity DataEC50:  37nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406376BDBM406376(2-((3,4-trans)-4-Hydroxy-3-(pyridin-2-ylmethyl)chr...)
Affinity DataEC50:  44nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406375BDBM406375(N-(Cyclopentylsulfonyl)-2-((3,4-trans)-4-hydroxy-3...)
Affinity DataEC50:  48nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406400BDBM406400(US10336733, Example 44)
Affinity DataEC50:  60nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406406BDBM406406(US10336733, Example 50)
Affinity DataEC50:  67nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406402BDBM406402(2-(Rac-trans)-4-Hydroxy-3-((2-phenyloxazol-4-yl)me...)
Affinity DataEC50:  75nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406392BDBM406392(US10336733, Example 37 | N-(tert-Butylsulfonyl)-2-...)
Affinity DataEC50:  81nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406360BDBM406360(4-Fluoro-2-((3S,4R or 3R,4S)-4-hydroxy-3-(pyridin-...)
Affinity DataEC50:  93nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406391BDBM406391(N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-...)
Affinity DataEC50:  95nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406367BDBM406367(N-(tert-Butylsulfonyl)-2-((3R,4S or 3S,4R)-4-hydro...)
Affinity DataEC50:  144nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406405BDBM406405(US10336733, Example 49)
Affinity DataEC50:  154nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406384BDBM406384(2-(Rac-trans)-4-Hydroxy-3-((1-methyl-1H-pyrazol-5-...)
Affinity DataEC50:  360nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406369BDBM406369(N-(tert-Butylsulfonyl)-4-fluoro-2-((3R,4S or 3S,4R...)
Affinity DataEC50:  441nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406371BDBM406371(N-(Cyclopropylsulfonyl)-4-fluoro-2-((3R,4S or 3S,4...)
Affinity DataEC50:  480nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406386BDBM406386(2-((Rac-trans)-3-((1-ethyl-1H-pyrazol-5-yl)methyl)...)
Affinity DataEC50:  538nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406387BDBM406387(N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-...)
Affinity DataEC50:  556nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406357BDBM406357(4-Fluoro-2-((3R,4S or 3S,4R)-4-hydroxy-3-(pyridin-...)
Affinity DataEC50:  650nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406385BDBM406385(2-((Rac-trans)-4-Hydroxy-3-((5-methyl-1,3,4-thiadi...)
Affinity DataEC50:  740nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406382BDBM406382(US10336733, Example 26)
Affinity DataEC50:  770nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406389BDBM406389(N-(tert-Butylsulfonyl)-2-((3R,4S or 3S,4R)-4-hydro...)
Affinity DataEC50:  808nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406366BDBM406366(4-Fluoro-2-((3R,4S or 3S,4R)-4-hydroxy-3-(pyridin-...)
Affinity DataEC50:  870nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406394BDBM406394(N-(tert-Butylsulfonyl)-2-((3R,4S or 3S,4R)-3-((1-e...)
Affinity DataEC50:  1.16E+3nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406363BDBM406363(2-((3R,4S or 3S,4R)-4-Hydroxy-3-(pyridin-2-ylmethy...)
Affinity DataEC50:  1.27E+3nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406359BDBM406359(4-Fluoro-2-((3R,4S or 3S,4R)-4-hydroxy-3-(pyridin-...)
Affinity DataEC50:  1.72E+3nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406377BDBM406377(2-((3R,4S or 3S,4R)-3-Benzyl-4-hydroxychroman-7-yl...)
Affinity DataEC50:  2.04E+3nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406361BDBM406361(N-(Cyclopropylsulfonyl)-2-((3R,4S or 3S,4R)-4-hydr...)
Affinity DataEC50:  2.17E+3nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 406379BDBM406379(2-((3R,4S or 3S,4R)-3-Benzyl-4-hydroxychroman-7-yl...)
Affinity DataEC50:  2.82E+3nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent