Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 8610
LigandChemical structure of BindingDB Monomer ID 408072BDBM408072(US10336774, Example 57 | US12053470, Compound 13)
Affinity DataIC50: 3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408073BDBM408073(US10336774, Example 58 | US12053470, Compound 14)
Affinity DataIC50: 4nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408094BDBM408094(US10336774, Example 88)
Affinity DataIC50: 4nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408096BDBM408096(US10336774, Example 90)
Affinity DataIC50: 4nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408075BDBM408075(US10336774, Example 60)
Affinity DataIC50: 4nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408086BDBM408086(US10336774, Example 77)
Affinity DataIC50: 5nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408058BDBM408058(US10336774, Example 43)
Affinity DataIC50: 6nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408057BDBM408057(US10336774, Example 42)
Affinity DataIC50: 7nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408067BDBM408067(US10336774, Example 52 | US12053470, Compound 11)
Affinity DataIC50: 7nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408078BDBM408078(US10336774, Example 63)
Affinity DataIC50: 7nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408076BDBM408076(US10336774, Example 61)
Affinity DataIC50: 7nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408097BDBM408097(US10336774, Example 91)
Affinity DataIC50: 8nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408071BDBM408071(US10336774, Example 56)
Affinity DataIC50: 9nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408063BDBM408063(US10336774, Example 48)
Affinity DataIC50: 9nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408093BDBM408093(US10336774, Example 87)
Affinity DataIC50: 9.30nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408066BDBM408066(US10336774, Example 51)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408082BDBM408082(US10336774, Example 67)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408098BDBM408098(US10336774, Example 92)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408034BDBM408034(US10336774, Example 3)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408069BDBM408069(US10336774, Example 54)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408074BDBM408074(US10336774, Example 59)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408091BDBM408091(US10336774, Example 86a)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408092BDBM408092(US10336774, Example 86b)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408095BDBM408095(US10336774, Example 89)
Affinity DataIC50: 11.8nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408079BDBM408079(US10336774, Example 64)
Affinity DataIC50: 13nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408087BDBM408087(US10336774, Example 78)
Affinity DataIC50: 15nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408048BDBM408048(US10336774, Example 15)
Affinity DataIC50: 16nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408083BDBM408083(US10336774, Example 73)
Affinity DataIC50: 20nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408062BDBM408062(US10336774, Example 47)
Affinity DataIC50: 21nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408088BDBM408088(US10336774, Example 79)
Affinity DataIC50: 23nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408033BDBM408033(US10336774, Example 2)
Affinity DataIC50: 25nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408035BDBM408035(US10336774, Example 4)
Affinity DataIC50: 32nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408061BDBM408061(US10336774, Example 46)
Affinity DataIC50: 38nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408055BDBM408055(US10336774, Example 27)
Affinity DataIC50: 42nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408089BDBM408089(US10336774, Example 80)
Affinity DataIC50: 42nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408060BDBM408060(US10336774, Example 45)
Affinity DataIC50: 44nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408054BDBM408054(US10336774, Example 22)
Affinity DataIC50: 53nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408084BDBM408084(US10336774, Example 74)
Affinity DataIC50: 56nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408081BDBM408081(US10336774, Example 66)
Affinity DataIC50: 65nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 38019BDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 70nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408070BDBM408070(US10336774, Example 55)
Affinity DataIC50: 73nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408038BDBM408038(US10336774, Example 7)
Affinity DataIC50: 73nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408037BDBM408037(US10336774, Example 6)
Affinity DataIC50: 74nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408085BDBM408085(US10336774, Example 76)
Affinity DataIC50: 78nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408077BDBM408077(US10336774, Example 62)
Affinity DataIC50: 100nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408050BDBM408050(US10336774, Example 17a)
Affinity DataIC50: 120nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408059BDBM408059(US10336774, Example 44)
Affinity DataIC50: 135nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408049BDBM408049(US10336774, Example 16)
Affinity DataIC50: 145nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408041BDBM408041(US10336774, Example 11b | US10336774, Example 10b)
Affinity DataIC50: 145nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408041BDBM408041(US10336774, Example 11b | US10336774, Example 10b)
Affinity DataIC50: 189nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

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