Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 8644
TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410174(US10370375, Example 22)
Affinity DataIC50: 10nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410170(US10370375, Example 18)
Affinity DataIC50: 21nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410178(US10370375, Example 26)
Affinity DataIC50: 34nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410177(US10370375, Example 25)
Affinity DataIC50: 71nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410174(US10370375, Example 22)
Affinity DataIC50: 130nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410174(US10370375, Example 22)
Affinity DataIC50: 260nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410170(US10370375, Example 18)
Affinity DataIC50: 390nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410180(US10370375, Example 28)
Affinity DataIC50: 550nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410154(US10370375, Example 2)
Affinity DataIC50: 582nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410153(US10370375, Example 1)
Affinity DataIC50: 838nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410178(US10370375, Example 26)
Affinity DataIC50: 840nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410176(US10370375, Example 24)
Affinity DataIC50: 930nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410177(US10370375, Example 25)
Affinity DataIC50: 1.10E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410170(US10370375, Example 18)
Affinity DataIC50: 1.20E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410179(US10370375, Example 27)
Affinity DataIC50: 1.80E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410154(US10370375, Example 2)
Affinity DataIC50: 1.89E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410165(US10370375, Example 13)
Affinity DataIC50: 2.00E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410178(US10370375, Example 26)
Affinity DataIC50: 3.00E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410180(US10370375, Example 28)
Affinity DataIC50: 3.20E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410177(US10370375, Example 25)
Affinity DataIC50: 3.60E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410154(US10370375, Example 2)
Affinity DataIC50: 4.59E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410153(US10370375, Example 1)
Affinity DataIC50: 5.51E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410165(US10370375, Example 13)
Affinity DataIC50: 6.00E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410179(US10370375, Example 27)
Affinity DataIC50: 7.80E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410153(US10370375, Example 1)
Affinity DataIC50: 7.93E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410176(US10370375, Example 24)
Affinity DataIC50: 8.50E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410157(US10370375, Example 5)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410157(US10370375, Example 5)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410157(US10370375, Example 5)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410158(US10370375, Example 6)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410155(US10370375, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410156(US10370375, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410156(US10370375, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410156(US10370375, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410155(US10370375, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410155(US10370375, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410162(US10370375, Example 10)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410162(US10370375, Example 10)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410163(US10370375, Example 11)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410163(US10370375, Example 11)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410161(US10370375, Example 9)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410161(US10370375, Example 9)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410161(US10370375, Example 9)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410162(US10370375, Example 10)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410159(US10370375, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410160(US10370375, Example 8)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410160(US10370375, Example 8)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410160(US10370375, Example 8)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410158(US10370375, Example 6)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM410158(US10370375, Example 6)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

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